[Wang Huanmin]
[Absract] Objective
The surgery of hepatobiliary cancer is rather complicated and dangerous so that new concepts and techniques should be adopted for improving its managements.As for rich blood supply of liver,the concept of bloodless procedure is particularly practical for hepatobliary surgery.Only through such a practice,safety of surgery may be guaranteed for enabling precision surgery.Through various kinds of techniques,precision surgery yields optimal outcomes with the smallest invasion and...
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[Dong Kuiran]
[Absract] Objective
Associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) has the characteristics of rapid increase in volume of liver remnant in a short period of time.It has been popularized in adult liver tumor surgery for the prediction of insufficient future liver remnant (FLR).Children¡¯s liver tumors are often relatively large,especially hepatoblastoma,which can invade multiple liver segments,or occupy the central anatomical site of the liver.Radical hepatectom...
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[Yao Wei, Dong Kuiran, Li Kai, Liu Gongbao, Bai Chenghao, Xiao Xianmin, Zheng Shan]
[Absract] Objective
Objective To explore the long-term therapeutic outcomes of hepatectomy for POST-TEXT (post-treatment extent of disease) ¢ó/¢ô hepatoblastoma.Methods From January 2009 to June 2019,clinical data were analyzed retrospectively for 37 children of POST-TEXT ¢ó/¢ô hepatoblastoma,including PRETEXT stage,alpha-fetoprotein (AFP),computed tomography (CT) or magnetic imaging imaging (MRI) findings,tumor resection mode and prognostic results.The survival rate was analyzed b...
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[Yang Wei, Ren Qinghua, Qin Hong, Chang Saishuo, Wang Huanmin]
[Absract] Objective
Objective To evaluate the outcomes of precision hepatectomy for pediatric hepatoblastoma (HB) and explore its choice of surgical approaches.Methods From June 2014 to May 2019,a total of 134 HB children undergoing precision hepatectomy were selected.Tumor stage,risk grade,tumor growth site,tumor size,preoperative chemotherapy,operative duration,intraoperative blood loss,postoperative serum levels of alanine aminotransferase (ALT) and aspartate aminotransferas...
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[Chen Zhixue, Dong Rui]
[Absract] Objective
Hepatoblastoma (HB) is a type of embryonal tumor of high malignancy usually occurring in children under 3 years of age.Surgical resection is the preferred option for HB.Complete surgical resection means better prognosis for tumor.Due to its sensitivity to chemotherapy,it can be treated by chemotherapy,radiotherapy and other treatment means.Currently,the mainstream chemotherapy program is C5V.Liver transplantation can be used for refractory HB,and there have been successful ca...
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[Cheng Jiwen1, Zhao Pu2, Yang Weili1, Zheng Baijun1, Pan Weikang1, Gong Wei1, Yu Qiang1, Li Peng1]
[Absract] Objective
Objective To explore the role and mechanism of let-7b and SALL4 in the malignant behaviors of hepatoblastoma (HB) cells. Methods Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was employed for defecting the expression of let-7b in normal liver cells (HL-7702),HB cell lines,HB tissues and adjacent normal tissues.Immunohistochemistry was applied for measuring the expression levels of SALL4 in HB tissues and paracancerous tissue and anal...
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[Li Ming, Li Yong, Huang Zhao, Tang Xianglian, Liu Zan, Zhou Yuxiang, Wen Jiabing, Xiang qiangxing]
[Absract] Objective
Objective To explore the inhibitory effect of small molecule inhibitor Serabelisib on the activity of PI3K Akt signaling pathway and its mechanism on the proliferation and apoptosis of human hepatoblastoma cell line.Methods Different concentrations of Serabelisib (0,2,4,8 ¦Ìmol/L) were employed for treating cells.The inhibition of cellular proliferation was detected by methyl thiazolyl tetrazolium (MTT).The changes of apoptosis were detected by flow cytometry...
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[Xie Huawei1, Zhang Weiling2, Liu Gang1, Zhang Jing1, Shen Zhou1, Xing Guodong1, Huang Liuming1, Hou Yanjun1]
[Absract] Objective
Objective To explore the surgical approaches and perioperative managements of pulmonary metastases in pediatric solid tumors.Methods Retrospective analysis was performed for the clinical data of 80 hospitalized children with pulmonary metastases of solid tumors from January 2012 to December 2018.Intraoperative findings,complications and outcomes were analyzed.Results A total of 114 resections of lung metastatic tumors were performed.The operative freq...
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[Zhu Tong, Li Lianyong, Liu Tianjing, Zhao Qun]
[Absract] Objective
Objective To measure the levels of vitamin D and bone metabolic markers and explore the correlation between prematurity,vitamin D and bone metabolic markers in neonates.Methods A total of 1,304 women delivered at Shengjing Hospital,China Medical University from November,2012 to October,2013.Finally 814 neonates including 24 very preterm,134 mildly preterm and 656 term were recruited for analysis.Enzyme-linked immunosorbent assay (ELISA) kit was utilized for ...
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[Liu Xuelai1, Li Long1, Li Suolin2, Xu Weili2, Cui Zhao3, Zhang Yongting4, Gao Peng5, Wei Yandong1, Li Jingna1, Zhang Wei1]
[Absract] Objective
Objective Folded peritoneum around orifice increases the difficulty during single-port laparoscopic percutaneous extraperitoneal internal ring closure (SPLPEC).The aim of this study was to explore the safety and feasibility of SPLPEC via previous separation and loosening deferens-external iliac vascular space using an inner grappler without hydrodissection for inguinal hernia in children. Methods Between November 2017 and December 2018,126 inguinal hernias c...
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[Yan Bing, Zhanghuang Chenghao, Tang Haoyu, Zhang Kun, Wu Chengchuang, Yao Zhigang]
[Absract] Objective
Objective To explore the effectiveness and necessity of pyeloureteroplasty for ureteropelvic junction obstruction in infants and toddlers.Methods The clinical data were retrospectively reviewed for 83 children undergoing open Anderson-Hynes procedure for hydronephrosis from July 2016 to June 2017.In conjunctions with the recent domestic and international literatures,the curative efficacy was evaluated from the perspectives of operative duration,amount of int...
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[Zhou Xiaobing, Li Bingxin, Chen Aijun, Zhou Xin, Guo Zhaokun]
[Absract] Objective
Objective To explore the clinical experience of three-dimensional (3D) laparoscopy in treatment of pediatric appendicural abscess.Methods A total of 26 cases of pediatric appendicural abscess underwent laparoscopy from January 2013 to August 2016.Three-Trocar technique was employed.Pus cavity was isolated and appendix located.Ultrasonic knife was used for dissecting appendiceal mesangium.After double ligating,appendiceal root was removed and a drainage tube ...
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[Yu Simiao1, Ma Lishuang2, Wang Ying2, Li Jingna2, Liu Chao2, Wei Yandong2, Qu Dong3, Zhang Hui4, Pan Shoudong5]
[Absract] Objective
Objective Congenital diaphragmatic hernia (CDH) refers to a structural birth defect of diaphragmatic defect.We performed a retrospective analysis and summarized the experiences of thoracoscopy for neonatal diaphragmatic hernia.Methods All children received prenatal consultations at the departments of obstetrics and pediatrics.Neonatal surgeons waited for delivery in delivery room.The children were transferred into SNICU of our center through a green channel ...
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[Yi Yinzhi, Xie Jianhui, Li Xiaoling, Xie Yonghong, Dong Lin]
[Absract] Objective
Objective To explore the application value of 10S management model in pediatric orthopedics ward.Methods A 10S management team was mobilized for conducting on-site management of pediatric orthopedics wards using the 10S management model,including finishing,rectificating,cleansing,cleaning,literacy,safety,economy,learning,service and satisfaction.The in-ward nursing quality and satisfaction were compared before and after implementation.Results After im...
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[Wu Xiaojuan, Yi Bin, Wang Xiaolin, Feng Jiexiong]
[Absract] Objective
Objective To analyze the clinical profiles of thyroglossal duct cyst with thyroid papillary carcinoma and explore the diagnostics and therapeutics of this rare disease.Methods Three girls were aged 27,53 and 9 years respectively.The major symptoms were cervical or submental cystic mass.One patient was diagnosed preoperatively as papillary thyroid cancer by fine needle puncture and bilateral total thyroidectomy was performed after a confirmation of intraopera...
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[Gao Zhongmin, Kong Lin]
[Absract] Objective
Objective To summarize a case of clinical nutrition specialist management program for a child with labiate intestinal fistula,severe malnutrition and depression after traffic accident injury.Methods Before fistula operation,double suction drainage and intravenous doses of somatotropin and somatostatin were performed.According to the psychological characteristics of post-traumatic depression,the preoperative appetite for food (limited semi-liquid diet) was sa...
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