Xie Huawei,Zhang Weiling,Liu Gang,et al.Surgical treatment of pulmonary metastases in pediatric solid tumors: a report of 80 cases[J].Journal of Clinical Pediatric Surgery,,19():415-419.[doi:10.3969/j.issn.1671-6353.2020.05.008]
Surgical treatment of pulmonary metastases in pediatric solid tumors: a report of 80 cases
- Keywords:
- Lung Neoplasms; Neoplasm Metastasis; Thoracoscopy; Surgical Procedures; Operative; Therapy; Child
- CLC:
- R726.1;R734.2;R73-37
- Abstract:
- Objective To explore the surgical approaches and perioperative managements of pulmonary metastases in pediatric solid tumors.Methods Retrospective analysis was performed for the clinical data of 80 hospitalized children with pulmonary metastases of solid tumors from January 2012 to December 2018.Intraoperative findings,complications and outcomes were analyzed.Results A total of 114 resections of lung metastatic tumors were performed.The operative frequency was once (n=58),twice (n=13),thrice (n=6) and fourth (n=3).The median follow-up period was 30(0.4-76) months.Among 28 deaths,21(75%,21/28) were due to tumor recurrence and metastasis and 7(25%,7/28) non-tumor causes.The latter included 2 perioperative deaths.The rates of cumulative overall survival (OS) at 1/3/5 year were 88.8%,81.0% and 58.6% respectively by Kaplan-Meier method and cumulative event-free survival (EFS) at 1/3/5 year 88.8%,74.5% and 52.1% respectively.Conclusion Some children with pulmonary metastatsectomy in solid tumors may benefit from surgery.And the safety and complications of pulmonary metastases can be controlled.The principles of thorough exploration and complete resection should be followed.
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Memo
收稿日期:2020-02-14。
基金项目:深圳医疗卫生三名工程（编号：SZSM201606088）
通讯作者:黄柳明,Email:surhlm@126.com