Home>>2023 03 issue list
[Zhan Jianghua, Wang Zhiru]
[Absract] Objective As a serious disease of hepatobiliary system in neonates and infants,biliary atresia (BA) is characterized by progressive inflammation and fibrosis of intra-and extrahepatic bile ducts.Kasai operation has remained a preferred treatment option.However,around 60% of children with postoperative liver fibrosis may progress further and eventually liver transplantation is often required for saving lives.Our current understandings of the etiology and pathogenesis of BA are insuffici... [MORE...]
[PDF:3055KB](207)
[Zhan Jianghua, Sun Rongjuan, Wang Zhiru, Zhang Ruifeng]
[Absract] Objective Through continuous explorations of pediatric surgeons in different countries,biliary atresia (BA) has gradually shifted from a deadly disease to one effectively managed by palliative surgery or liver transplantation.It is imperative for clinicians to standardize the diagnostic and therapeutic procedures of BA children to smoothly transition from children to adults.As promulgated by Japanese Biliary Atresia Society (JBAS) in 2021,English version of the Guidelines was elaborate... [MORE...]
[PDF:5352KB](213)
[Liu Kunhui, Gong Yiming, Cai Wei]
[Absract] Objective Objective To evaluate the efficacy of currently popular Nomogram prediction model for biliary atresia (BA) through a single-center data model.Methods Retrospective review was preformed for 631 children undergoing surgical explorations for infantile obstructive jaundice from 2009 to 2020.According to the findings of intraoperative cholangiography,they were assigned into two groups of BA (n=500) and non-BA (n=131).Gender,body weight,ALP (alkaline... [MORE...]
[PDF:4703KB](136)
[Zhang Kaizhi, Chen Yutong, Zheng Zebing, Tang Chengyan, Gong Yuan, Huang Lu, Zhou Wankang, Liu Yuanmei, Jin Zhu]
[Absract] Objective Objective To explore the application value of ultrasonic measurement of hilar cyst size in differentiating between cystic biliary atresia (CBA) and congenital biliary dilatation (CBD).Methods Retrospective review was conducted for clinical data of 34 hospitalized children with hilar cysts aged <150 days from January 2013 to January 2022.According to the findings of intraoperative cholangiography,they were assigned into two groups of CBA (n=14) and ... [MORE...]
[PDF:4945KB](127)
[Han Yijiang1, Wu Hao1, Ji Haosen1, Chen Baohai2, Hu Shuqi1, Zhao Xiaoxia1, Tou Jinfa1]
[Absract] Objective Objective To explore the correlation between age of Kasai portoenterostomy and early prognosis to provide references for timing of Kasai surgery in biliary atresia (BA) children.Methods Retrospective review was conducted for clinical data of hospitalized BA children from January 2019 to December 2021.General profiles (gender & operative age) and parameters of liver function,coagulation function and blood ammonia were collected.According to the jaundice c... [MORE...]
[PDF:4233KB](139)
[Zhao Yilin1, Wu Xiaoxia2, Xu Xiaodan1, Zhan Jianghua1]
[Absract] Objective Objective To explore the impact of cytomegalovirus (CMV) infection on the prognosis of Kasai operation in children with biliary atresia (BA).Methods From January 2018 to December 2020,91 BA children undergoing Kasai operation at Tianjin Children¡¯s Hospital and Shanxi Children¡¯s Hospital were divided into two groups of CMV positive (n=35) and CMV negative (n=56).CMV positive children were divided into antiviral treatment and non-treated groups.F... [MORE...]
[PDF:3982KB](128)
[Zhou Hui, Li Suolin, Shi Baojun, Zhong Zhiyong, Fang Yanbin, Yang Xiaofeng]
[Absract] Objective Objective To explore the hepatic expression of platelet-derived growth factor-BB (PDGF-BB),Snail 1 and epithelial-mesenchymal transition (EMT) in children of biliary atresia (BA) and examine the relationship among three parameters.Methods From January 2018 to December 2019,there were BA (n=25),choledochal cysts (CCC,n=15) and liver tumors (NL,n=10).After collecting biopsy tissues,immunohistochemistry and real-time fluorescent quantitativ... [MORE...]
[PDF:3949KB](91)
[Wu Xiaoxia, Liu Wenyue, Sun Xue, Jin Yuanyuan, Ren Hongxia]
[Absract] Objective Objective To explore the risk factors and outcomes of recurrent cholangitis after Kasai in biliary atresia (BA) patients.Methods Retrospective review was conducted for clinical and follow-up data of 60 BA children with cholangitis after Kasai procedure from January 2018 to September 2021.According to whether the frequency of cholangitis episodes was more than or equal to 3 times in half a year,they were divided into two groups of recurrent cholangitis (n<... [MORE...]
[PDF:3252KB](137)
[Wang Wenjuan1, Yang Shuai2, Zhou Zhaokai2, Lyu Lei2, Zhang Yanpin2, Wen Yibo2, Lu Wei3, Wang Qingwei2, Wen Jianguo2, Yang Jing4]
[Absract] Objective Objective To quantitatively evaluate the changes of lower urinary tract symptoms (LUTS) and psychological behavior in children with tethered cord syndrome (TCS) before and after tethered cord release and explore the effects of deterring surgery (DS) on LUTS and psychological behavior.Methods From January 2020 to May 2022,43 patients with TCS and DS diagnosed by MRI were retrospectively reviewed.According to the results of Lower Urinary Tract Dysfunction Rese... [MORE...]
[PDF:3212KB](134)
[Xu Xiaogang, Zeng Jixiao, Liu Fei, Lan Menglong, Tao Boyuan, Liang Zijian, Zhou Shaoyun, Lin Yuzhen]
[Absract] Objective Objective To explore the feasibility,safety and prognosis of air enema plus scarless mini-invasive surgery for secondary intussusception in children.Methods From January 2018 to January 2021,clinical data were retrospectively reviewed for 19 children with secondary intussusception undergoing reduction by air enema and scarless mini-invasive surgery (transumbilical single-port laparoscopy or electronic colonoscopy).One group (n=9) caused by colonic pol... [MORE...]
[PDF:4517KB](127)
[Lin Jing, Zhao Jie]
[Absract] Objective Objective To explore the clinicopathologic differences between thyroid cancer (TC) in children and adolescents versus adults and examine gene mutation,prognosis and risk factors of TC in children and adolescents.Methods For this retrospective study,84 TC children and adolescents aged ¡Ü20 years hospitalized from June 2007 to December 2021 were included as observation group while 100 adult TC in-patients during the same period as control group.The similarities... [MORE...]
[PDF:4310KB](121)
[Wen Jiabing, Li Yong, Xiao Yaling, Li Ming, Tang Xianglian]
[Absract] Objective Objective To explore the value of lymph node biopsy in screening children with lymphoma-associated hemophagocytic syndrome (HPS).Methods From January 1,2012 to December 31,2021,clinical data were retrospectively reviewed for 513 HPS children and 808 children with lymph node biopsy.They were divided into biopsy and non-biopsy groups while lymphoma-negative children with HLH biopsy were classified as biopsy-negative group and those with a diagnosis of lymphoma... [MORE...]
[PDF:3607KB](100)
[Zhang Yalong, Lin Yan, Hui Yaxing, Zhang Anding, Zeng Lingchao, Wang Chunhui, Guo Hongwei, Zhang Xinhui, Jiang Xun]
[Absract] Objective Objective To evaluate the efficacy and safety of modified endoscopic retrograde appendicitis therapy (mERAT) for acute uncomplicated appendicitis in children.Methods From October 2018 to May 2021,clinical data were retrospectively reviewed for 228 hospitalized children of acute uncomplicated appendicitis.They were followed up by telephone and outpatient and inpatient electronic information systems in June 2022.The follow-up time was 19(15,22) months.Clinical... [MORE...]
[PDF:4590KB](124)
[Hu Weize, Dai Yujian, Zheng Huiming, Liu Zhen, Ye Tong, Wang Yingjun]
[Absract] Objective Objective To explore the method and efficacy of single-port laparoscopic percutaneous extraperitoneal closure using self-made hernia needle for pediatric inguinal hernia.Methods From September 2018 to June 2020,clinical data were retrospectively reviewed for 715 children of pediatric inguinal hernia undergoing single-port laparoscopic percutaneous extraperitoneal closure using self-made hernia needle.There were 580 boys and 135 girls.The involved side was un... [MORE...]
[PDF:3584KB](154)
[Shao Jiawen1, Zhou Pingjiang1, Zhou Lingling2, Li Zhongrong1]
[Absract] Objective Objective To explore the characteristics,diagnosis,treatment and prognosis of eosinophilic solid and cystic renal cell carcinoma in children.Methods Retrospective analysis was performed for clinical data of a child with eosinophilic solid and cystic renal cell carcinoma.The databases of PubMed and Web of Science were searched with the key words of "eosinophilic solid and cystic renal cell carcinoma" or "eosinophilic solid and cystic renal cell cancer" or "eo... [MORE...]
[PDF:3784KB](113)
[Li Yuye1, Cong Lining1, Li Yulou1, Wang Zan2, Zhang Qiang3, Zhang Xiaojun3, Fu Xingjiao3]
[PDF:2493KB](89)
[Cao Huiyan, Feng Jiexiong]
[Absract] Objective Poor nutritional status not only affects clinical prognosis,but also causes irreversible developmental damage in children.Despite heightened clinical attention to nutrition and improved managements in recent years,the overall incidence of childhood malnutrition has declined year by year.However,due to a double blow of disease and operation,children undergoing surgery face high nutritional risks and nutritional status is prone to deteriorate.Moreover,inadequate nutritional man... [MORE...]
[PDF:4206KB](141)
[Chen Xinyuan, Li Zhi]
[Absract] Objective Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor in children.Clinical manifestations of IMTs are associated with mass tumor effect and local inflammatory responses and differ according to tumor location.Surgical resection is an optimal treatment option with a high recurrence rate.IMT remains insensitive to chemoradiotherapy.With rapid developments of next-generation sequencing and targeted drug dosing,clinicians have acquired a deeper understanding of its ... [MORE...]
[PDF:3982KB](102)