[Zhan Jianghua1, Chen Yajun2]
[Absract] Objective
Biliary atresia is one of severe hepatobiliary diseases in infancy and surgery has remained a sole option of saving lives.Currently a sequential treatment of Kasai operation and liver transplantation is practiced.However,with the technological development of liver transplantation in children,the curative effect of liver transplantation has significantly improved.The role of kasai operation is relonsidered.This review summarized the evolutions,results,advantages and disadvanta...
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[Wu Xiaoxia, Ren Hongxia, Jin Yuanyuan, Zhang Hui, Liu Wenyue]
[Absract] Objective
Objective To explore the risk factors of native liver survival (NLS) time under 2 years after Kasai operation for biliary atresia (BA).Methods Clinical and follow-up data were retrospectively analyzed for all children undergoing Kasai operation for BA from January 2009 to June 2017.According to whether or not NLS time was under 2 years,they were divided into survival and death groups.BA classification,gender,cytomegalovirus (CMV) infection,age at Kasai,posto...
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[Yao Taoyue, Duan Xingxing, Zhou Mengjie, Yang Liu, Chen Wenjuan]
[Absract] Objective
Objective To explore the diagnostic value of ultrasonic shear wave elastography (SWE) in combination with blood biochemical indicators to biliary atresia (BA).Methods Infants within 90 days who were suspected with cholestatic hepatopathy received conventional ultrasonography (US) and SWE for measuring liver stiffness measurement (LSM).Blood biochemical indicators were collected within 3 days from SWE examination.They were divided into BA (n=24) and no...
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[Jiang Jingying1, Ju Zhaoru2, Sun Yinghua2, Shen Zhen1, Chen Gong1, Zheng Shan1]
[Absract] Objective
Objective To determine the value of shear wave elastography (SWE) in the diagnosis of biliary atresia (BA) through a meta-analysis of the relevant recent researches.Methods According to the retrieval criteria,the Chinese and English database literature was searched and the articles were screened and selected.The included literature was evaluated by the QUADAS-2 scale.The relevant data were extracted and SROC curve was plotted.Results A total of 132 re...
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[Qiao Qi, Zhang Zhibo]
[Absract] Objective
Biliary atresia (BA) is a disease of progressive inflammation and fibrosis of intra/extrahepatic bile ducts in infants.Its etiology and mechanism of progression have remained ill elucidated.Kasai portoenterostomy (KPE) is a first choice for biliary atresia.Successful KPE operation may reconstruct bile drainage.However,the long-term native liver survival (NLS) after KPE operation is relatively low and children often suffer from various complications.Most children require liver...
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[Huang Zihan, Zheng Shan]
[Absract] Objective
As a common diseases in pediatric surgery,biliary atresia (BA) is difficult for an early diagnosis and has an unsatisfactory prognosis.Gamma-glutamyltransferase (GGT),as a key enzyme involved in glutathione metabolism,is widely found in various tissues of human body.It is located on the external surface of cellular membranes.GGT in liver is mainly located on the cytoplasm of hepatocyte and intrahepatic biliary epithelial cells.Blockage of bile duct system due to BA causes an ...
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[Luo Cheng, Gao Zhipeng, Dong Zhan, Lou Yue]
[Absract] Objective
Objective To explore the clinical manifestations,pathological features,diagnoses,treatments and outcomes of pediatric Kaposiform hemangioendothelioma (KHE) of bone.Methods A case of pediatric KHE of bone was reported along with more cases from the databases of Wanfang,Weipu,CNKI,PubMed and Medline prior to May 2020.Results The lesion of this child was originally derived from calcaneal.After a definite diagnosis through biopsy and pathological examinat...
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[Zhao Ping, Liu Xiang, Zuo Wei, Gao Wei, Zhang Yanmin, Li Qingzhi, Wu Gongjing, Wu Di, Zhao Mengtian, Ge Dahai]
[Absract] Objective
Objective To explore the relevant influencing factors of recurrence after thoracoscopic repair of congenital diaphragmatic hernia (CDH) in neonates and its treatment effect on recurrence.Methods Clinical data were analyzed retrospectively for 45 CDH neonates undergoing thoracoscopic repair from January 2013 to July 2019.The relevant factors related to postoperative recurrence were statistically analyzed.Results Eight cases recurred with a total postop...
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[Li Sen, Pan Weihua, Tan Xiang, Wang Jun]
[Absract] Objective
Objective The association of anorectal malformation (ARM) with Hirschsprung¡¯s disease (HD) is rare so that a misdiagnosis is frequent in clinical practices.The objective was to improve understanding through its clinical diagnosis and treatment.Methods From September 2003 to October 2019,a total of 3 boys with perineal fistula ARM were associated with HD.More clinical cases were retrieved from the databases of Wanfang,Weipu,CNKI,PubMed and Medline up until Oc...
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[Li Ming, Li Yong, Huang Zhao]
[Absract] Objective
Objective To explore the clinical features,diagnosis and treatment of multiple ileal diverticulum and intestinal duplication in children.Methods A total of 546 children with Meckel¡¯s diverticulum or intestinal duplication were treated.There were 6 cases of multiple ileal diverticulums or diverticulum associated intestinal duplication.Their clinical data were collected and analyzed retrospectively.Results The clinical manifestations were gastrointestin...
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[Duan Jiahua, Zheng Pengfei, Hu Xinyue, Tang Kai, Lou Yue]
[Absract] Objective
Objective To compare the clinical outcomes after open reduction with and without femoral shortening for children aged 2 to 3 years with Tonnis grade ¢ò developmental dysplasia of the hip(DDH).Methods From January 2016 to December 2017,48 children aged 2 to 3 years with Tonnis grade ¢òDDH(48 hips)were retrospectively reviewed.There were 21 hips in femoral non-shortening group and 27 hips in femoral shortening group.The average age was 28.6(25-34)months.The Seve...
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[Shen Yiding1, Zhu Linfeng1, Wang Xiaohao1, Ru Wei1, Zhao Yijun1, Chen Guangjie1, Huang Yong1, Tang Daxing1, Xu Shan2]
[Absract] Objective
Objective To retrospectively analyze the treatment outcomes of recurrent penile curvature after hypospadias repair.Methods From 2010 to 2019,36 children with recurrent penile flexion after hypospadias repair were treated.Angle of penile flexion was measured with a protractor after artificial erection test.Penile flexion was treated according to the correction strategy.Penile flexion was completely ungloved and penile flexion stretched after removing scar tis...
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[Yue Yuhang, Li Lianyong]
[Absract] Objective
Lower limb long bone fractures of femoral and tibial shafts are common in children.Frequent overgrowth at injured side may cause leg length inequality,low back pain,scoliosis and sciatica.The mechanism of overgrowth is probably related with the disruption of periosteum after fracture.The post-fracture periosteum reduces the pressure on growth plate and stimulates bone growth.Overexpression of related genes after fracture promotes proliferation and differentiation of chondrocy...
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[Wang Huaikeng, Li Nanzhu]
[Absract] Objective
Brodie bone abscess occurs frequently in metaphyses of long bones of four extremities of children and adolescents.The common pathogens are Staphylococcus aureusthe and Streptococcus.Due to non-typical symptoms and signs at the time of onset,inflammatory parameters may be normal or slightly elevated.A definite diagnosis is often difficult.Once diagnosed,it should be treated as soon as possible.Simple drugs or combined drug-surgery options may be selected.Most treatment outcome...
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[Zhou Ying, Yang Shaobo, Huang Yanlei]
[Absract] Objective
Anorectal malformation (ARM) is a common digestive tract malformation in pediatric surgery.Currently surgery is the most important treatment.However,some ARM children have varying degrees of defecation dysfunction and it affects postoperative quality-of-life.Although the specific pathogenesis of ARM and the mechanism of postoperative defecation dysfunction have remained elusive,the development of nervous system (enteric nervous system,ENS) in intestinal wall of terminal rectu...
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