Yang Wen,Zhou Qixing,Cheng Qi,et al.The discussion over pathological features and the effect of surgical treatment of children with giant pigmented nevus.[J].Journal of Clinical Pediatric Surgery,,17():131-135.
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The discussion over pathological features and the effect of surgical treatment of children with giant pigmented nevus.

Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R] volume: 第17卷 Number: 2018 02 Page: 131-135 Column: 论著 Date of publication: 2018-02-28
Author(s):
Yang Wen1; Zhou Qixing1; Cheng Qi1; Han Kun1; Zhang Yong1 ; Chen Jun1; Wu Dingan1; Fan Lifang2.
1.Department of PlasticSurgery,Wuhan Childrens Hospital（Wuhan Maternal and Child Healthcare Hospital）, Tongji Medical College, Huazhong University of Science & Technology,Wuhan,Hubei 430016,China;
Keywords:
Nevus/CN;  Surgical Procedures; Operative;  Therapy;  Pathology;  Child
Document code:
A
Abstract:
ObjectiveTo explore the association among surgical techniques,surgical timing and pathological features of children Giant Pigmented Nevus.Methods28 cases with Giant Pigmented Nevus on children who were treated in our deparment from June 2009 to December 2014,were retrospectively analyzed.These cases include 18 males and 10 females,in which 13 cases on the head and face region and 15 cases on the body and limb region.The samples are stained by using HE staining.One case of infants with giant pigmented nevi inside the hairline was cured by twostage operation with the skin expander;23 patients received fullthickness skin graft to fix the defect after excision of giant nevus;one case undertook resection surgery in different stages,with graft covering the wound;Three cases of older children undertook partial resection due to the large area of nevi,which was crossing the joints and lacking of enough skin for grafting.ResultsResected giant nevus had better blood supply than the normal skin.Subcutaneous lipid was rare due to the association with the superficial fascia.HE staining pathological examination showed that 2 cases were melanocytes borderline nevus (7%),26 cases were compound nevus (93%),and no malignant change was occurred.In 28 cases,all the wounds were healed in I stage,and the healing was satisfactory.ConclusionCongenital giant nevus has the cellular biological characteristics of benign tumors,and early plastic surgery can effectively reduce the surgical scar.Surgery can better restore the shape and function of children,remove the area and need less tissue,and reduce the risk of malignant transformation in pathology,to a large extent,reduce the psychological harm of patients.
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