KAI1/CD82表达水平与肾母细胞瘤转移的相关性研究
- 文献标志码:
- A
- 摘要:
- ?目的探讨KAI1/CD82与肾母细胞瘤转移的相关关系。方法选取38例确诊为肾母细胞瘤的组织蜡块标本，按有无转移分为两组，采用免疫组织化学的方法检测KAI1/CD82的表达。结果肾母细胞瘤中无转移组和有淋巴结或远处转移组的KAI1/CD82阳性表达率分别为5385%、3333%，两者差异有统计学意义；Ⅰ、Ⅱ、Ⅲ、Ⅳ期肾母细胞瘤中，KAI1/CD82阳性表达率分别为6250%、5833%、3333%、3333%，各组间差异无统计学意义。无转移组和有淋巴结或远处转移组中，化疗组与未化疗组分别比较，差异均无统计学意义（P>005）。结论肾母细胞瘤中KAI1/CD82的阳性表达率与肿瘤是否转移有关，与临床分期及术前是否化疗无关。
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