[Zheng Shan]
[Absract] Objective
The diagnosis and treatment of children with biliary atresia (BA) in China mainland have significantly improved.However,long-term native liver survival rate and quality of life should be further optimized.Long-term standard follow-ups of Kasai postoperative complications and liver fibrosis,comprehensive treatments with multidisciplinary cooperations,long-term monitoring of growth and development,reasonable nutrition and vaccination guidance and appropriate timing for liver tr...
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[Chen Gong, Zhu Ye, Wu Shaojing]
[Absract] Objective
Abnormal bile acid metabolism in biliary atresia (BA) may injure hepatocytes and bile duct epithelial cells.Ursodeoxycholic acid is currently a standard postoperative drug for BA.However,its efficacy and dosing have remained controversial.Steroidal bile acid nuclear receptor activation (obeticholic acid,etc),non-steroidal nuclear receptor agonist (LJN-452,etc),intestinal bile acid reabsorption related protein regulating drug (A4250,etc),liver bile acid transporter and kidney ...
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[Zhan Jianghua1, Yu Chen2]
[Absract] Objective
The formulations of clinical treatment consensus and guidelines are based upon scientific and efficient multicenter researches.The multicenter researches of pediatric surgery in China have remained in a developing stage.There are still such practical problems as late start,little practice and unbalanced regional development.For promoting the overall sophistication level of pediatric surgery to achieve standardization and synchronization,the author summarized the domestic and ...
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[Luo Haiyan1, Li Shuangjie1, Li Bixiang2, Zhou Chonggao2, Qiu Jun3, Chen Weiting1]
[Absract] Objective
Objective To evaluate the diagnostic value of applying transient elastography for children with liver fibrosis.Methods Retrospective studies were conducted for 153 hospitalized children of chronic hepatitis B and biliary atresia admitted from January 1,2015 to December 31,2018 and from January 1,2016 to December 31,2018 respectively.The values of liver stiffness measurement (LSM) by transient elastography and their general profiles were collected.They were d...
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[Shen Qiulong, Chen Yajun, Peng Chunhui, Pang Wenbo, Wang Zengmeng, Wu Dongyang, Wang Kai]
[Absract] Objective
Objective To explore the value of liver stiffness measurement(LSM)in predicting five-year native liver survival after Kasai procedure in children with biliary atresia(BA).Methods From April 2012 to February 2013,31 cases of BA undergoing Kasai operation were analyzed retrospectively.There were 11 boys and 20 girls.The LSM and liver function were collected before operation and at 2/4/8 weeks after operation.Liver fibrosis was graded according to liver patholo...
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[Long Qi1, Tou Jinfa2, Chen Fei1, Zhang Ting1, Qin Qi2, Wang Wenqiao1, Ma Ming1]
[Absract] Objective
Objective To explore the nutritional status of children with excellent liver autogenous survival after Kasai surgery for biliary atresia (BA) for personalized nutritional interventions.Methods A retrospective survey was conducted for 46 BA children surviving well with autologous liver at 1 year after Kasai surgery.Clinical data were collected for age,height/body length,weight and serum levels of fat-soluble vitamins.The Z scores of height-for-age (HAZ),weigh...
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[Wei Yuanyuan, Fan Jinnan, Li Yarui]
[Absract] Objective
Objective To systematically evaluate the association between single nucleotide polymorphism of rs17095355 genetic susceptibility and biliary atresia (BA).Methods The literature retrieval was conducted by searching the English databases (PubMed,EMbase & Web of Science) and Chinese databases (CNKI,Wanfang,VIP & SinoMed) for the publications on the association between single nucleotide polymorphism of rs17095355 genetic susceptibility and BA by late Jul...
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[Liu Xiang, Cao Hongyan, Qiao Li, Zhang Qi, Shi Lei]
[Absract] Objective
Objective To evaluate the efficacy of sodium acetate ringer on fluid therapy in biliary atresia (BA) children.Methods A total of 60 children aged 21 to 65 days,American Society of Anesthesiologists physical status¢ò/¢ó,scheduled for elective Kasai surgery under general anesthesia were randomized divided into LR:sodium lactate ringer¡¯s injection group and AR:sodium acetate ringer¡¯s injection group(n=30 each).The concentrations of sodium ion,potassium ion...
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[Lu Yunan, Lin Ran, Pan Yuancheng, Chen Shunyou, Lin Qingjian]
[Absract] Objective
Objective To explore the approach and efficacy of closed reduction K-wire and cannulated screw internal fixation for adolescent T-type intercondylar fractures of humerus.Methods T-type intercondylar humeral fractures were analyzed retrospectively.Eighteen cases underwent closed reduction and internal fixation with K-wire and cannulated screw and elbow joints were fixed with high polymer plaster for 4-6 weeks.When imaging examination indicated at a statisfact...
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[Fan Ming1,2, Mo Xuming1,2, Chen Jun3, Sun Jian1,2, Peng Wei1,2, Qi Jirong1,2, Wu Kaihong1,2]
[Absract] Objective
Objective To review the clinical efficacy of mitral valve reconstruction for mitral regurgitation in children.Methods From January 2012 to January 2019,clinical data were collected for 202 children with congenital mitral insufficiency undergoing mitral reconstruction.The improvements of left ventricular function and mitral regurgitation before and after surgery were evaluated by echocardiography and the follow-up outcomes were analyzed.There were 84 boys and...
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[Lin Xiangshang, Deng Licai, Yao Jiaxing, Wang Tao, Chen Xindi, Wang Qian]
[Absract] Objective
Objective To explore the clinical protocols and efficacies of lymphatic malformation and examine the efficacy and safety of interventional sclerotherapy for lymphatic malformation.Methods A total of 29 children with focal lymphatic malformations on head,neck,trunk and extremities were recruited.Age of treatment,choice of sclerosing agent and sclerotherapy were reviewed.The volume or size of cyst before and after treatment was evaluated and classified into th...
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[Wu Shuihua1, Chen Zhaohui1, Fan Shuangshi1, Zou Xin1, Shen Chenfu2]
[Absract] Objective
Objective To explore the clinical characteristics,diagnostic and therapeutic strategies,pathological characteristics and prognosis of infantile intracranial aneurysm (IIA).Methods Retrospective analysis was performed for clinical data of a 2-month-old IIA child.And the relevant literature reports were retrieved from the databases of PubMed,SpringerLink,Google Scholar,CBM,CNKI,WANFANG and CQVIP.Results In this study,a 2-month-old child underwent transc...
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[Li Lijing, Zhang Jianmin, Hu Jing, Ren Yi, Gao Jia, Wang Fang]
[Absract] Objective
Objective To explore the correlation between cerebral state index (CSI) and bispectral index (BIS) in the monitoring of radiofrequency ablation anesthesia in children and evaluate the feasibility of CSI for pediatric monitoring.Methods Thirty-six children aged 7 to 15 years,ASA ¢ñ to ¢ò,were scheduled for arrhythmic radiofrequency ablation under general anesthesia.Propofol 2.5 mg/kg,cis-atracurium 0.1 mg/kg and fentanyl 1 ¦Ìg/kg were administered for induction....
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[Wang Min, Zhao Sijun, Xiao Zhirong, Huang Min, Peng Xiangyue, Xie Jun]
[Absract] Objective
Objective To explore the independent risk factors of congenital microtia (CM) through an epidemiological survey.Methods With a case-control study design from June 2016 to June 2018,a total of 80 CM children were assigned into case group for auricular reconstruction.And another 80 children of exudative otitis media were selected as control group.Through parental interviews and questionnaire survey,social demographic profiles,peripartum living environment,dise...
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[Zhou Chengxiao, Qi Shiqin, Bian Jian, Pan Deng]
[Absract] Objective
Objective To explore the clinical characteristics,diagnosis and treatment of blunt hepatic trauma in children.Methods From December 2012 to June 2018,retrospective analysis was performed for clinical data of 42 children with blunt hepatic trauma.They were divided into non-operative (n=34) and interventional therapy (n=8) groups.Both groups were analyzed with regards to patient history,clinical manifestations,combined injuries or not,changes of ...
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[Dai Shiyi1, Peng Suhua1, Chen Siyuan2, Ji Yi1]
[Absract] Objective
As a rare,endotheliogenic and locally aggressive vascular neoplasm appearing predominantly in infants and toddlers,kaposiform hemangioendothelioma (KHE) is characterized by diffuse and invasive vascular and lymphatic proliferation.It may be associated with thrombocytopenia,hypofibrinemia and coagulation factor consumption,which is also known as Kasabach-Merritt phenomenon (KMP).KMP can cause serious complications and even death.With the continuous progress of pathogenesis,cli...
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[Zhong Jiafei1, Gu Shuo2]
[Absract] Objective
With a rapid progress of imaging and other techniques,perinatal management of neural tube defects (NTDs) has undergone a quantum leap over the last three decades.Previously NTDs were only discovered at birth or underdiagnosed so that there were a high mortality and a poor prognosis.Current advances in prenatal diagnosis and targeted management have led to a renewal of perinatal management including active preventions,intensive prenatal examinations and consultations,selection...
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