Home>>2025 10 issue list
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[901£­904] From guidelines to practice: Reflections on standardizing treatments of Wilms tumor in children
[Liu Xin, Yang Yi]
DOI:10.3760/cma.j.cn101785-202507007-001
[Absract] Objective Wilms tumor (WT) is the most common kidney tumor in children.Thanks to comprehensive protocols involving surgery plus adjuvant/neoadjuvant chemoradiotherapy when necessary,the overall survival rate of WT children has significantly improved.Despite a generally favorable prognosis for most cases,some still face the risks of lower survival rates or long-term treatment-related side effects.These risks are related not only to tumor¡¯s inherent biological characteristics but also no... [MORE...]
[PDF:5406KB](325)
[905£­915] Chinese expert consensus on surgical management of unilateral Wilms tumor
[Groups of Oncologic Surgery & Urology, Branch of Pediatric Surgery, Chinese Medical Association]
DOI:10.3760/cma.j.cn101785-202507051-002
[Absract] Objective Wilms tumor (WT) is the most common primary malignant renal tumor in children.Currently,there is no unified consensus on certain surgical principles for WT,particularly in complex cases such as large tumors,invasion of adjacent organs,nephron-sparing procedures,and lymph node biopsy.Non-standardized surgical procedures can lead to tumor recurrence and upstaging,which has drawn increasing clinical concern.Standardizing the surgical approach and protocols for WT is therefore of... [MORE...]
[PDF:11993KB](463)
[916£­922] Development of a preoperative imaging-based predictive model for nephron-sparing surgery feasibility in pediatric bilateral Wilms tumor and comparative evaluation of multiscore systems
[Li Jiayi, Li Zonghan, Fang Yiwei, Li Xin, Yu Bo, Shi Jianhan, Liu Wen, Hu Xinxuan, Yang Yang, Zhang Weiping, Sun Ning, Song Hongcheng, Li Zhenwu]
DOI:10.3760/cma.j.cn101785-202501058-003
[Absract] Objective Objective To construct a clinical prediction model for the feasibility of nephron-sparing surgery (NSS) in children with bilateral Wilms tumor (BWT) based upon preoperative imaging data and compare it with existing adult renal tumor preoperative scoring systems. Methods A retrospective analysis was conducted for the clinical and imaging data of surgical BWT children from 2008 to 2024.A total of 121 renal units from 61 children were included (99 in NSS group ... [MORE...]
[PDF:7136KB](238)
[923£­928] Study on the prognostic impact of preoperative glomerular filtration rate assessment in children with Wilms tumor
[Fan Xu, Yin Xiaoming, Liu Xin, Yang Yi]
DOI:10.3760/cma.j.cn101785-202507028-004
[Absract] Objective Objective To investigate the impact of accurate preoperative glomerular filtration rate (GFR) measurement on the prognosis of children with unilateral Wilms tumor. Methods This retrospective cohort study included 54 children with pathologically confirmed unilateral Wilms tumor treated at Shengjing Hospital of China Medical University from January 2017 to December 2023.Clinical data were collected,including age at diagnosis,gender,National Wilms Tumor Study-5... [MORE...]
[PDF:5243KB](290)
[929£­933] Prognostic factors of stage ¢ó favorable-histology Wilms tumor
[Liu Pei, Yang Yang, Zhang Weiping, Song Hongcheng, He Yuzhu, Tian Jun, Li Minglei, Sun Ning]
DOI:10.3760/cma.j.cn101785-202306011-005
[Absract] Objective Objective To explore the prognostic differences of children with stage ¢ó favorable-histology Wilms tumor (FHWT) of different staging factors and histological subtypes. Methods From March 2008 to June 2020,the clinicopathological data were retrospectively reviewed for 45 children of stage ¢ó FHWT.Event-free survival rate (EFS) and overall survival rate (OS) of children with different stage ¢ó factors and histological subtypes were compared. Results There... [MORE...]
[PDF:4579KB](196)
[934£­939] Treatments and prognoses of recurrent Wilms¡¯ tumor in children: a retrospective study at a single center
[Cui Kongkong, Yang Shuhan, Tian Xiaomao, Wei Yi, Dong Junjun, He Xingyue, Wu Shengde, Zhang Deying, Hua Yi, Liu Xing, Lin Tao, He Dawei, Shi Qinlin, Wei Guanghui]
DOI:10.3760/cma.j.cn101785-202507009-006
[Absract] Objective Objective To explore the risk factors associated with recurrence and prognoses of Wilms tumor (WT). Methods A retrospective analysis was conducted for the relevant clinical data of 250 WT children admitted from January 2004 to December 2023.They were assigned into two groups of recurrence (n=32,12.8%) and non-recurrence (n=218,87.2%).Gender,age at presentation,tumor stage,subtype,history of preoperative chemotherapy and metastatic status at dia... [MORE...]
[PDF:5662KB](195)
[940£­945] Factors related to an initial episode of cholangitis after Kasai procedure in patients with biliary atresia
[Xie Hua, Lu Zhengchen, Ding Zequan, Tang Weibing]
DOI:10.3760/cma.j.cn101785-202405071-007
[Absract] Objective Objective To explore the associated factors for an initial episode of cholangitis within 6 months after Kasai procedure (KPE) in patients with Type ¢ó biliary atresia (BA). Methods From January 2021 to March 2023,the relevant clinical data were retrospectively reviewed for 111 children with type ¢ó BA undergoing KPE with complete 1-year follow-ups.Age at KPE,gender,perioperative blood biochemical parameters,liver fibrosis grade,timing of an initial episode of ... [MORE...]
[PDF:6307KB](210)
[946£­951] Analysis of factors influencing reintervention after surgical repair of aortic arch anomalies in children
[Gong Hainan1, Zhang Rufang2, Chen Xiaolong2, Xie Yewei2, Li Xiaobing2]
DOI:10.3760/cma.j.cn101785-202405017-008
[Absract] Objective Objective To investigate the factors influencing the need for reintervention after surgical repair of aortic arch anomalies in children. Methods A total of 128 children operated for aortic arch anomalies in the Department of Cardiothoracic Surgery at Shanghai Children¡¯s Hospital from January 2009 to December 2020 were retrospectively analyzed.Patients were divided into two groups based on whether they underwent a second surgery or interventional balloon angi... [MORE...]
[PDF:5612KB](248)
[952£­956] Diagnosis and treatment of recurrent tracheoesophageal fistula after surgery for type ¢ó congenital esophageal atresia
[Li Bo, Dong Jie, Zhao Fan, Ma Tidong, Zou Chanjuan, Xu Guang, Zhou Chonggao]
DOI:10.3760/cma.j.cn101785-202502044-009
[Absract] Objective Objective To explore the preoperative diagnostic modalities for recurrent tracheoesophageal fistula (rTEF) after type ¢ó congenital esophageal atresia repairing and evaluate the feasibility of intraoperative identification of fistula location via pressurized ventilation through a tracheal tube. Methods A retrospective analysis was conducted for medical records of 8 children diagnosed and treated for type ¢ó esophageal atresia with rTEF from 2010 to 2024.Preope... [MORE...]
[PDF:5457KB](240)
[957£­962] Analysis of factors associated with cyst rupture in pediatric hepatic cystic echinococcosis
[Su Xun1, Li Wanfu2, Liu Hui2, Fan Jiarong2, Ma Zhu2, Aerxin Habuding2, Ayiguzaili Maimaijiang2]
DOI:10.3760/cma.j.cn101785-202308004-010
[Absract] Objective Objective To explore the factors associated with cyst rupture in pediatric hepatic cystic echinococcosis,and provide clinical reference for diagnosis and treatment. Methods A retrospective analysis was conducted on the clinical data of 100 pediatric patients with hepatic echinococcosis treated in the Department of Pediatric General Surgery at the First Affiliated Hospital of Xinjiang Medical University from 2017 to 2023.Based on whether cyst rupture occurred... [MORE...]
[PDF:6116KB](193)
[963£­968] Clinical diagnosis and treatment analysis of solid pseudopapillary neoplasm of the pancreas in children
[Ji Siqi, Yan Xueqiang, Duan Xufei, Qin Xinke, Zhu Zhenchuang, Kuang Houfang]
DOI:10.3760/cma.j.cn101785-202410041-011
[Absract] Objective Objective To summarize the clinical experience in the diagnosis and treatment of solid pseudopapillary neoplasm of the pancreas in children. Methods A retrospective analysis was conducted on clinical data from 15 pediatric patients with pancreatic solid pseudopapillary neoplasm treated in the Department of General Surgery at Wuhan Children¡¯s Hospital,Tongji Medical College,Huazhong University of Science and Technology,from July 2007 to January 2024.The cohor... [MORE...]
[PDF:6586KB](382)
[969£­974] Effect of dexmedetomidine nasal spray on emergence agitation in children undergoing eye surgery
[Zhang Shuibing, Kang Xin, Chen Zheng, Du Zhen]
DOI:10.3760/cma.j.cn101785-202503114-012
[Absract] Objective Objective To observe the effect of dexmedetomidine nasal spray on emergence agitation in children undergoing eye surgery. Methods Children fulfilling the inclusion criteria for elective eye surgery were randomized into two groups of dexmedetomidine nasal spray (DS) and saline nasal spray (NS).Both groups received intranasal dosing at 20 min before anesthesia induction.The incidence of emergence agitation in postanesthesia care unit(PACU)was recorded at 10 mi... [MORE...]
[PDF:5443KB](326)
[975£­980] Application of nasal intubation using self-shaping endotracheal tube under video laryngoscopy in pediatric daytime dental caries treatment
[Lu Tingting, Sun Fei, Cai Weiwei, Zhang Li, Zhong Zhiqiu]
DOI:10.3760/cma.j.cn101785-202408016-013
[Absract] Objective Objective To evaluate the value of nasotracheal intubation using a self-shaping endotracheal tube under video laryngoscopy in ensuring airway safety and procedural efficiency during pediatric day-case dental caries treatment. Methods A total of 120 pediatric patients undergoing elective day-case dental caries treatment under general anesthesia in the Department of Stomatology,Affiliated Children¡¯s Hospital of Nanjing Medical University,from February 2024 to ... [MORE...]
[PDF:5775KB](189)
[981£­987] Effects of glucose metabolism through a targeted inhibition of PFKFB3 on hemangioma-derived endothelial cell
[Xiang Shanshan1, Gong Xue1, Zhou Jiangyuan1, Qiu Tong1, Zhang Jing2, Yang Kaiying3, Ji Yi1]
DOI:10.3760/cma.j.cn101785-202412032-014
[Absract] Objective Objective To explore the effects of targeted inhibition of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) on glucose metabolism in hemangioma-derived endothelial cells (HemECs). Methods HemECs without intervention were utilized as control group while HemECs intervened by PFKFB3 inhibitor PFK15 designated as experimental group.HemECs from control and experimental groups were subjected to targeted glucose metabolomics using high-performance chr... [MORE...]
[PDF:8633KB](270)
[988£­990] Treatment of infantile testicular lymphangioma by testis-sparing surgery: one case report
[Yang Ye1, Zhang Jingti2, Xu Ke1]
DOI:10.3760/cma.j.cn101785-202503081-015
[PDF:3189KB](201)
[991£­994] Research advances on using pMRI for predicting avascular necrosis after closed reduction in developmental dislocation of the hip
[Liu Yanhan, Xu Hongwen]
DOI:10.3760/cma.j.cn101785-202409064-016
[Absract] Objective Developmental dislocation of the hip (DDH) is one of the most common congenital deformities of the lower limbs in children.Currently,closed reduction under general anesthesia followed by spica cast fixation is the first-line treatment for DDH in children aged 6 to 24 months.However,avascular necrosis (AVN) of the femoral head remains a major complication following closed reduction.There is a growing evidence that gadolinium-enhanced perfusion magnetic resonance imaging (pMRI)... [MORE...]
[PDF:4489KB](192)
[995£­1000] Research advances in children with megacystis-microcolon-intestinal hypoperistalsis syndrome
[Fang Wenjuan, Li Fangyuan, Peng Guo, Li Shoulin]
DOI:10.3760/cma.j.cn101785-202308005-017
[Absract] Objective Megacystis-microcolon-intestinal hypoperistalsis syndrome is a rare congenital disease characterized by megacystis,microcolon and weakened or absent intestinal peristalsis with a poor prognosis.Most children die from severe sepsis,end-stage renal dysfunction and long-term malnutrition.Currently there is no effective therapy and its pathogenesis has remained elusive.It may be related to genetic factors,neurogenic,myogenic,hormones and other related aspects.This review summariz... [MORE...]
[PDF:7031KB](246)