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[701－705] Twodecades of diagnosis and treatment of anorectal malformations in children: a paradigm shift from anatomical reconstruction to functional rehabilitation

[Chen Yajun]

DOI:10.3760/cma.j.cn101785-202507043-001

[Absract] Objective Congenital anorectal malformations are common gastrointestinal anomalies in children,and the strategies used for their diagnosis and treatment directly influence long-term outcomes.Over the past two decades,with the advancement of minimally invasive techniques,deeper understanding of embryonic development,and the refinement of functional assessment systems,the core concept in managing congenital anorectal malformations has shifted from solely anatomical reconstruction toward ... [MORE...]

[PDF:6244KB](1052)

[706－712] Prenatal diagnosis of congenital digestive tract anomalies and assessing its clinical value

[Zhang Minzhong¹, Wang Jun^1,2]

DOI:10.3760/cma.j.cn101785-202412069-002

[Absract] Objective Congenital digestive tract anomalies are a diverse class of structural abnormalities occurring during fetal development.It not only affects the quality-of-life of neonates but also threatens their lives.With the rapid developments of such medical technologies as high-resolution ultrasoound,fetal magnetic resonance imaging and next-generation sequencing,a growing number of digestive tract anomalies may be detected and diagnosed prenatally.Timely and accurate prenatal diagnosis... [MORE...]

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[713－720] Expert Consensus on Diagnosing Biliary Atresia and Kasai Surgery Based Upon Endoscopic Technology (Edition 2025)

[Expert Committee on Pediatric Endoscopy, National Health Commission, Branch of Medical Robotic Surgeon, Chinese Medical Doctor Association]

DOI:10.3760/cma.j.cn101785-202410003-003

[Absract] Objective In the clinical practices of surgery,technology continues to drive innovation in diagnostic and surgical modalities.Laparoscopic technique plays a more and more important role in the diagnosis and treatment of biliary atresia (BA).As one of the more groundbreaking innovations,da Vinci robotic surgical system not only changes the way surgery is performed,but also opens up new therapeutic options for BA.Robotic-assisted Kasai portoenterostomy,as a treatment option for BA,has ac... [MORE...]

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[721－728] Comparison of the efficacy of two-stage versus three-stage laparoscopic-assisted anorectoplasty in the treatment of congenital anorectal malformations

[Zhang Haoyuan^1,2,3, Zhang Jingmin^2,4, Zhou Yan⁵, Li Long^1,3]

DOI:10.3760/cma.j.cn101785-202502056-004

[Absract] Objective Objective To compare the medium-and long-term outcomes of two-stage versus three-stage laparoscopic-assisted anorectoplasty (LAARP) for the treatment of congenital anorectal malformations (ARMs). Methods A retrospective analysis was conducted on 254 pediatric patients with intermediate to high-type ARMs who underwent LAARP at the Department of General Surgery,Capital Center for Children‘s Health between June 2007 and December 2019.Patients were divided into ... [MORE...]

[PDF:7505KB](1007)

[729－733] Prognostic observation of rectal prolapse after surgery for congenital anorectal malformations and analysis of risk factors for recurrence

[Hu Wenshu¹, Li Long^1,2]

DOI:10.3760/cma.j.cn101785-202504066-005

[Absract] Objective Objective To evaluate the prognosis of anorectal prolapse (ARP) following surgery for congenital anorectal malformations (ARMs) and to analyze the risk factors associated with ARP recurrence. Methods A retrospective analysis was conducted on 114 pediatric patients with ARP following ARMs surgery,treated in the Department of Pediatric Surgery at the Capital Center for Children‘s Health,Capital Medical University,between January 2015 and June 2024.Postoperativ... [MORE...]

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[734－740] Clinical characteristics and surgical management of total colorectal duplication in children

[Yan Jun, Chen Yajun, Peng Chunhui, Pang Wenbo, Wu Dongyang]

DOI:10.3760/cma.j.cn101785-202503001-006

[Absract] Objective Objective To explore the clinical characteristics,diagnostic approaches,and surgical treatment strategies for total colorectal duplication in children. Methods A retrospective analysis was conducted on pediatric patients with total colorectal duplication who were surgically treated at Beijing Children‘s Hospital,Capital Medical University,from January 2010 to December 2024.Additionally,relevant literature published between 2000 and 2024 was reviewed using th... [MORE...]

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[741－744] Individualized surgical management and rehabilitation of perineal single-orifice cloaca in infants and young children

[Wang Rui, Peng Kun, Ma Tidong, Zhuang Yan]

DOI:10.3760/cma.j.cn101785-202310049-007

[Absract] Objective Objective To summarize individualized surgical techniques,postoperative rehabilitation,and follow-up for perineal single-orifice cloaca in infants and young children,providing a reference for its diagnosis and treatment. Methods The clinical data of 5 patients with single-orifice cloaca treated at Hunan Children‘s Hospital between October 2016 and October 2023 were reviewed retrospectively.Pre-operative findings,diagnostic work-up,operative procedures,postop... [MORE...]

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[745－751] Analysis of risk factors for progression of periventricular-intraventricular hemorrhage in preterm infants with gestational age ＜ 32 weeks

[Hong Fei¹, Zhang Min², Han Shuping², Chu Xiaobin¹, Zhang Yuhan³, Chen Xiaoqing³, Wang Huaiyan⁴, Chen Dongmei⁵, Pan Zhaojun⁶, Ye Danni⁷, Jiang Shanyu⁷, Xu Yan⁸, Liu Songlin⁹]

DOI:10.3760/cma.j.cn101785-202406010-008

[Absract] Objective Objective To investigate potential risk factors for the progression of periventricular-intraventricular hemorrhage (PIVH) in preterm infants with gestational age <32 weeks. Methods A retrospective study was conducted on clinical data from infants with gestational age <32 weeks admitted to the neonatal intensive care units (NICUs) of 20 hospitals in the Jiangsu Neonatal Perinatal Cooperative Network between January 1,2020 and December 31,2022.Infants we... [MORE...]

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[752－757] Effect of hyperbaric oxygen therapy plus goal-directed training on MRI-SWI,GMFM,balance and ADL in cerebral hemorrhage children

[Duan Yaqin¹, Zhang Jinwei², Hu Jihong¹, Liu Juan¹, Wu Shuihua², Liang Dazhong³]

DOI:10.3760/cma.j.cn101785-202409045-009

[Absract] Objective Objective To explore the effect of hyperbaric oxygen therapy (HBOT) plus target-oriented planning (GDT) on children during the recovery phase of intracerebral hemorrhage (ICH). Methods For this prospective study,30 children with spontaneous ICH were treated at Hunan Children‘s Hospital between January 2020 and December 2023.Based upon the specific inclusion and exclusion criteria,they were randomized into either HBOT+GDT group (n=15) or conventional p... [MORE...]

[PDF:5743KB](882)

[758－763] Clinical efficacy of enhanced recovery after surgery plus robot-assisted laparoscopy for congenital biliary dilatation in children

[Li Wei¹, Luo Jingchu¹, Hu Hai², Jia Xuqin³, Qin Yinying³, Chen Jiabo¹, Chen Peng¹, Luo Yige¹]

DOI:10.3760/cma.j.cn101785-202402027-010

[Absract] Objective Objective To explore the efficacies of combining perioperative measures of enhanced recovery after surgery (ERAS) with robot-assisted laparoscopy in children with congenital biliary dilatation (CBD). Methods Between January 2015 and December 2021,retrospective analysis was performed for the relevant clinical data of 81 hospitalized CBD children.They were categorized into three groups based upon specific treatment options.Group A underwent traditional periope... [MORE...]

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[764－770] Preoperative serum levels of IL-1β,I-FABP and PRDX1 in children with Hirschsprung‘s disease and their predictive values for postoperative enterocolitis

[Zhang Haisheng¹, Men Nan², Li Xuequn¹]

DOI:10.3760/cma.j.cn101785-202404039-011

[Absract] Objective Objective To explore the serum levels of interleukin-1β (IL-1β),intestinal fatty acid binding protein (I-FABP) and peroxiredoxin-1 (PRDX1) in children with Hirschsprung‘s disease (HD) and examine their predictive values for postoperative Hirschsprung associated enterocolitis (HAEC). Methods From June 2021 to June 2023,178 HD children were recruited and another 150 healthy children undergoing physical examinations were regarded as control group.According to t... [MORE...]

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[771－775] Preliminary experience with Kareem procedure in the surgical correction of pediatric intestinal malrotation

[Huang Hua¹, Ma Shuaijun¹, Ma Xiaoyu¹, Ma Shaobin³, Xue Han¹, Chen Xuanxuan¹, Huang Hongwei¹, Yuan Yang¹, Chen Qi¹, Feng Jiexiong²]

DOI:10.3760/cma.j.cn101785-202501008-012

[Absract] Objective Objective To preliminarily explore the feasibility and safety of the Kareem procedure in correcting intestinal malrotation in children. Methods A retrospective analysis was conducted on clinical data of 13 pediatric patients with intestinal malrotation treated with the Kareem procedure in the Department of Neonatal Surgery at the Third Affiliated Hospital of Zhengzhou University from January to November 2024.Data collected included general patient informatio... [MORE...]

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[776－780] Hereditary multiple exostosis with hemopneumothorax:a report of two case with a literature review

[Yang Guozhu¹, Su Yi¹, He Chaosheng¹, Ji Yanhui¹, Liu Mingxue¹, Li Suolin^1,2]

DOI:10.3760/cma.j.cn101785-202404038-013

[Absract] Objective Objective To summarize the clinical features,diagnostics and treatments of hereditary multiple exostosis (HME) with hemopneumothorax in children. Methods From December 2022 to April 2023,the relevant clinical data were reviewed for 2 HME children with hemopneumothorax admitted into First Affiliated Hospital of Xiamen University.A systematic review of literature was performed through searching the databases of PubMed,Medline,Web of Science,China National Know... [MORE...]

[PDF:5254KB](892)

[781－785] Treatment of renal artery aneurysm related to neurofibromatosis type 1 with renal autotransplantation in children:one case report with a literature review

[Zhao Yijun, Zhu Linfeng, Yang Fan, Chen Guangjie]

DOI:10.3760/cma.j.cn101785-202502006-014

[Absract] Objective Objective To explore the clinical characteristics,diagnostics and treatments of renal artery aneurysm related to neurofibromatosis type 1,as well as the prognosis of pediatric renal autotransplantation. Methods Retrospective analysis was performed for clinical data of a child with renal artery aneurysm related to neurofibromatosis type 1,who underwent renal autotransplantation.The databases of PubMed,MEDLINE,Web of Science,Wanfang,China National Knowledge In... [MORE...]

[PDF:5248KB](897)

[786－792] Therapeutic effect and related mechanisms of bone marrow mesenchymal stem cell-derived exosomes on giant colon model rats

[Guo Bohua¹, Wang Jianfeng², Zhang Yinan¹, Zhang Jianfeng¹, Fan Changhe¹, Huang Chan¹, Tong Guoyu¹, Zeng Xiangyong³]

DOI:10.3760/cma.j.cn101785-202502059-015

[Absract] Objective Objective To explore the therapeutic effect of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) on the model of megacolon in rats and elucidate its related mechanisms. Methods BMSCs from bone marrow of normal Sprague-Dawley (SD) rats were isolated,cultured and purified in vitro by total bone marrow adhesion.Exosomes were isolated from BMSCs supernatant by ExoQuick reagent method.Thirty SD rats were randomized into model group (megacolon rat m... [MORE...]

[PDF:7373KB](907)

[793－795] A case report of synchronous multiple primary cancers: mediastinal ganglioneuroblastoma with left adrenocortical carcinoma in a child

[Ji Fengming¹, Zhang Huangchenghao¹, Zhang Kun¹, Song Yuanhua², Yan Bing¹, Yang Zhen²]

DOI:10.3760/cma.j.cn101785-202309014-016

[PDF:3479KB](807)

[796－800] Research advances in etiology and diagnosis of congenital scoliosis

[Zhang Cefei, Hu Weiming, Xu Ke, Liu Fuyun]

DOI:10.3760/cma.j.cn101785-202401005-017

[Absract] Objective Congenital scoliosis (CS) is caused by an abnormal progressive development of spine during embryonic period,including failures of vertebral formation and segmentation.The pathogenesis of CS is rather complex so that it is correlated mainly with multiple genetic and environmental factors.An early diagnosis of CS is dependent upon fetal ultrasonic screening,postnatal anterior-lateral radiography of whole spine,plain scan & three-dimensional computed tomography (CT) reconstr... [MORE...]

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