Home>>2026 04 issue list
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[301£­309] Expert Consensus on Single-Site Laparoscopy in Children (Edition 2025)
[Expert Committee of Pediatric Endoscopy, National Health Commission; Branch of Pediatric Surgery, Chinese Medical Doctor Association; Group of Endoscopic Surgery, Branch of Pediatric Surgery, Chinese Medical Association]
DOI:10.3760/cma.j.cn101785-20251122-00078
[Absract] Objective With rapid advancement of science and technology and continuous innovation of surgical instruments,pediatric surgery has now entered the area of minimally invasive surgery (MIS).Laparoendoscopic single-site surgery (LESS) is gaining popularity.To further standardize and enhance the proficiency of pediatric surgeons in MIS procedures in China,National Health Commission¡¯s Expert Committee on Pediatric Endoscopy,Branch of Pediatric Surgeon,Chinese Medical Doctor Association and ... [MORE...]
[PDF:9917KB](327)
[310£­315] Application value of Trapdoor surgical approach for pediatric neuroblastoma at cervicothoracic junction
[Chen Ming1, He Min1, Wu Xuan1, Cai Jiabin1, Tang Yinbing1, Xiong Jieni1, Lu Dongfang1, Liu Ming1, Meng Jinwen1, Wang Qi1, Wang Yuwei1, Ding Zheyu1, Hou Li1, Tao Ting1,2, Mao Junqing1, Zhang Lifeng1, Wang Jinhu1]
DOI:10.3760/cma.j.cn101785-20260309-00101
[Absract] Objective Objective To evaluate the technical essentials,safety and clinical application value of Trapdoor surgical approach for neuroblastoma at cervicothoracic junction in children.Methods From January 2018 to December 2025,the relevant clinicopathological data were retrospectively reviewed for 72 children with neuroblastoma at cervicothoracic junction operated via a Trapdoor approach.Surgical-related parameters and postoperative complications were recorded.And the ... [MORE...]
[PDF:5651KB](261)
[316£­322] Proteomic profiling-based clinical risk analysis and molecular subtypic identification in neuroblastoma
[Chen Kai, Wu Zhixiang, Wu Yeming]
DOI:10.3760/cma.j.cn101785-20251228-00138
[Absract] Objective Objective Neuroblastoma (NB) is characterized by profound clinical heterogeneity.Current clinical indicators have failed to fully elucidate its complex biological nature.This study was intended to utilize in-depth proteomic analysis to resolve the molecular features of NB,refine risk stratifications and identify potential therapeutic targets.Methods A cohort of 150 NB children was enrolled for deep characterization using high-throughput quantitative proteomi... [MORE...]
[PDF:9327KB](258)
[323£­332] Prognostic value of fibrinogen-to-albumin ratio in children with neuroblastoma
[Xi Chengjun, Yang Chao]
DOI:10.3760/cma.j.cn101785-20260107-00009
[Absract] Objective Objective To explore the prognostic value of preoperative fibrinogen-to-albumin ratio (FAR) in children with neuroblastoma (NB).Methods Between January 2014 and January 2025,retrospective analysis was conducted for the relevant clinical data of 279 NB children.They were randomized into two cohorts of training (n=195) and validation (n=84).The optimal cutoff value for FAR was determined by receiver operating characteristic (ROC) curve analysis.U... [MORE...]
[PDF:8807KB](328)
[333£­343] Construction and validation of a prognostic model for neuroblastoma based upon glycosyltransferase genes
[He Shiqing1,2, Wang Meide1,3, Sha Yongliang1,2]
DOI:10.3760/cma.j.cn101785-20260124-00038
[Absract] Objective Objective To construct and validate a prognosis model for neuroblastoma (NB) based on glycosyltransferases (GTs).Methods GEO85047 from the Gene Expression Omnibus (GEO) database was used as training set while the TARGET database as validation set.Based upon 213 GTGs reported in the literature,single/multi-factor Cox regression analysis,protein-protein interaction (PPI) and least absolute shrinkage and selection operator (LASSO) regression were employed for s... [MORE...]
[PDF:14644KB](263)
[344£­354] Effect of PPAR¦Á-regulated HADHA on biological behavior of human wilms tumor
[Wang Zhi, Tu Lei, Ning Feng, He Jun, Zhao Yaowang]
DOI:10.3760/cma.j.cn101785-20260112-00019
[Absract] Objective Objective To explore the effects and regulatory mechanisms of PPAR ¦Á and HADHA on biological behaviors of human nephroblastoma cells,including proliferation,apoptosis and migration.Methods The authors downloaded the GEO database nephroblastoma sequencing dataset GSE138869,screened for differentially expressed genes and performed enrichment analysis; Collected clinical samples of nephroblastoma and adjacent tissues and employed Western Blot and qRT PCR to det... [MORE...]
[PDF:14490KB](277)
[355£­359] Treatment decision-making and short-term outcomes for hepatoblastoma based upon tumor volume proportion
[Li Zhuo1, Cheng Lin2, Han Lulu3, Wang Yi1, Liu Qi1, Dong Qian1,4, Chen Xin1]
DOI:10.3760/cma.j.cn101785-202507010
[Absract] Objective Objective To explore the timing of surgery and treatment strategies for hepatoblastoma (HB) children with varying tumor volume proportions through examining the correlation between tumor size and treatment selection,thereby providing evidence for optimizing clinical decision-making.Methods For this retrospective case series study,the relevant clinical data were collected from 59 HB children between January 2014 and December 2024.All of them underwent Hisense... [MORE...]
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[360£­364] Age dependence and stratification characteristics of FOHR in children with hydrocephalus
[Zhang Jinwei1, Wu Shuihua1, Yuan Liping2, Yang Zhiguo3]
DOI:10.3760/cma.j.cn101785-202510005
[Absract] Objective Objective To evaluate the age dependence of frontal occipital horn ratio (FOHR) in children with hydrocephalus and compare FOHR with Evans index (EI) in parallel.The distribution characteristics of FOHR under different etiologies,anatomical and physiological types and age stratification were explored to provide rationales for clinical quantitative evaluation.Methods A retrospective analysis was conducted for the relevant clinical data of 223 children with hy... [MORE...]
[PDF:4908KB](239)
[365£­370] Comparative efficacy analysis of pneumovesical modified nipple versus Cohen ureteral reimplantation for infantile primary obstructed megaureter
[Zhu Guodong, Liu Xingjian, Li Aiwu]
DOI:10.3760/cma.j.cn101785-20251030-00028
[Absract] Objective Objective To compare the clinical outcomes and safety of pneumovesical modified nipple ureteral reimplantation versus pneumovesical Cohen ureteral reimplantation for primary obstructed megaureter (POM) in infants.Methods For this retrospective cohort study,the relevant clinical data were retrospectively reviewed for 56 POM infants from January 2015 to October 2024.According to specific surgical approaches,they were assigned into two groups of Cohen (n... [MORE...]
[PDF:6019KB](237)
[371£­376] Clinical outcomes of pneumovesicoscopic ureteral reimplantation for ureterovesical junction obstruction in young infants aged under 6 months
[Wang Hao, Gui Meng, He Qingbao, Zhang Lingling, He Hongjia, Li Kaisheng, Zhang Lei]
DOI:10.3760/cma.j.cn101785-20251124-00085
[Absract] Objective Objective To evaluate the safety and efficacy of pneumovesicoscopic ureteral reimplantation for ureterovesical junction obstruction (UVJO,also known as primary nonrefluxing megaureter) in young infants aged <6 month.Methods A single-center retrospective cohort study was conducted for 77 UVJO children from January 2019 to December 2023.They were assigned into two groups of young infant (<6 month,n=19) and older infant (¡Ý6 month,n=58).The s... [MORE...]
[PDF:5628KB](257)
[377£­381] Clinical efficacy of suspension training plus Schroth exercise for mild idiopathic scoliosis in school-aged children
[Li Xiaofei1, Yin Xi1, Hu Niyuan2, Xie Yiming3, Zhang Zibei4, Chen Ailian1]
DOI:10.3760/cma.j.cn101785-202602010-00064
[Absract] Objective Objective To explore the clinical efficacy of suspension training plus Schroth exercise for mild idiopathic scoliosis in school-aged children.Methods For this randomized controlled trial,46 children with scoliosis underwent rehabilitation interventions at Department of Rehabilitation Medicine,Hunan Provincial People¡¯s Hospital between July 2024 and August 2025.They were randomized into two groups of control and treatment (n=23 each).Control group rece... [MORE...]
[PDF:4890KB](659)
[382£­386] Management strategies for corrosive tracheoesophageal fistula and concurrent esophageal stricture in children
[Gu Yichao, Hua Kaiyun, Liao Junmin, Zhao Yong, Li Shuangshuang, Sun Dayan, Wang Dingding, Zhang Yanan, Huang Jinshi]
DOI:10.3760/cma.j.cn101785-202503105
[Absract] Objective Objective To explore the management strategies and outcomes of corrosive tracheoesophageal fistula (TEF) with or without esophageal stricture in children.Methods For this retrospective case series,the relevant clinical data were retrospectively reviewed for 10 hospitalized children of corrosive TEF between October 2018 and October 2024.There were 4 boys and 6 girls.The causes were button batteries (n=7) and non-button battery corrosive agents (n[MORE...]
[PDF:4504KB](234)
[387£­390] Nutritional therapy for ultra-short bowel syndrome in neonates: one case report
[Zheng Yuanyuan1, Zhang Lan2, Xiao Mili2, Dong Rui3, Yao Wei3, Yang Tongling4, Tang Zifei5, Wang Jin2, Zhang Rong2, Zheng Shan3, Shen Chun6, Qian Tian1]
DOI:10.3760/cma.j.cn101785-202502033
[Absract] Objective Short bowel syndrome (SBS) is a major cause of intestinal failure in children.And nutritional management has been a core prognostic factor.The goal of treatment is to improve intestinal function and promote intestinal adaptation.SBS with a remaining small intestine length of <25 cm or <10% of expected length for age is termed as ultra-short bowel syndrome.Nutritional support for this condition is more challenging.This review focused upon the diagnosis,treatment and nutr... [MORE...]
[PDF:4036KB](215)
[391£­395] Recent advances in urinary biomarkers related to posterior urethral valves
[Li Yahong1,3, Liu Yang2, Lin Houwei2,3]
DOI:10.3760/cma.j.cn101785-202409056
[Absract] Objective Posterior urethral valve (PUV) is a common cause of lower urinary tract obstruction in boys.Despite valve ablation in early childhood,some patients may progress to end-stage renal disease (ESRD).Currently no reliable biomarkers are available in clinical practice for predicting the potential of developing ESRD.Detected more easily and earlier than other types,urinary-derived biomarkers may become early diagnostic and prognostic markers for renal outcomes in PUV children.This r... [MORE...]
[PDF:5793KB](265)
[396£­400] Research advances on applying whole exome sequencing for genetic diagnosis of fetal ventriculomegaly
[Song Weian, Gu Shuo]
DOI:10.3760/cma.j.cn101785-20260205-00052
[Absract] Objective Fetal ventriculomegaly (FVM) is one of central nervous system (CNS) abnormalities with a high detection rate on prenatal ultrasound.Its etiology has remained rather complex and genetic factors play some crucial roles.Traditional prenatal genetic diagnostic techniques of chromosomal karyotyping and chromosomal microarray analysis (CMA) have relatively hindered diagnostic yields for identifying the etiology of isolated FVM.Whole exome sequencing (WES),a high-throughput sequenci... [MORE...]
[PDF:5929KB](235)