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[Zhang Yi, Li Hao]
[Absract] Objective
Posthemorrhagic hydrocephalus following intraventricular hemorrhage is a common and severe complication in preterm infants,and its clinical management requires multidisciplinary collaboration and stage-specific decision-making.This review systematically summarizes the pathophysiological mechanisms of the disease,highlighting posthemorrhagic inflammatory responses and cerebrospinal fluid circulation impairment as keycontributors to ventricular dilation and secondary brain inju...
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[Wu Shuihua]
[Absract] Objective
With advances in perinatal medicine and neonatal intensive care technologies,the survival rates of extremely preterm infants and extremely low birth weight infants have increased significantly; however,brain injury in preterm infants remains a major constraint on long-term quality of survival.Germinal matrix-intraventricular hemorrhage (GMH-IVH) and its secondary complications,including posthemorrhagic ventricular dilatation (PHVD) and posthemorrhagic hydrocephalus (PHH),are ...
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[Diao Yangyang, Zhang Yutai, Li Chaoran, Liang Ping, Ji Wenyuan]
[Absract] Objective
Objective To investigate the independent risk factors for secondary hydrocephalus after neonatal germinal matrix-intraventricular hemorrhage and to construct an individualized risk prediction nomogram model. Methods A single-center retrospective study was conducted including neonates with germinal matrix-intraventricular hemorrhage admitted to the Children¡¯s Hospital of Chongqing Medical University between November 2020 and June 2025. According to the occurr...
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[Li Hao, Chen Zhaohui, Fan Shuangshi, Zhou Xiangyue, Su Jun, Wu Shuihua]
[Absract] Objective
Objective To explore the risk factors for poor prognosis after initial Ommaya reservoir implantation in neonates with posthemorrhagic hydrocephalus (PHH) secondary to intracranial hemorrhage,and to provide evidence for clinical management and prognostic evaluation. Methods A retrospective analysis was conducted on the clinical data of 39 neonates with PHH who underwent initial Ommaya reservoir implantation in the Department of Neurosurgery,Children¡¯s Hospita...
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[Zhang Luyi, Zhang Gang, Zhang Yuhang, Shi Hangyu]
[Absract] Objective
Objective To investigate the clinical efficacy of continuous external ventricular drainage in the treatment of severe intraventricular hemorrhage in neonates and to evaluate long-term neurofunctional outcomes. Methods This retrospective case-control study included 49 neonates with severe intraventricular hemorrhage.According to the treatment strategy,patients were divided into a surgical group (n=32),who underwent implantation of a ventricular reservo...
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[Yuan Liping1, Wu Shuihua2, Hu Jihong1, Zhang Jinwei2]
[Absract] Objective
Objective To identify the factors associated with cerebral palsy (CP) after neonatal intracranial hemorrhage and construct and evaluate an early prediction model. Methods A single-center retrospective study was conducted for 79 neonates with complete records undergoing rehabilitation assessment/intervention between January 2020 and June 2024.Based upon the follow-up outcomes,they were assigned into two groups of CP (n=22) and non-CP (n=57).Peri...
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[Liu Bo1, Deng Ke2, Xie Shigang1, Wang Weiwei1, Wang Guangyu1]
[Absract] Objective
Objective To analyze the main clinical manifestations,causes of hemorrhage,surgical approaches,and postoperative complications of intracranial hemorrhage in full-term neonates,and to improve clinical understanding and diagnostic and therapeutic management of this condition. Methods A retrospective analysis was conducted on 37 full-term neonates with intracranial hemorrhage who were admitted and underwent surgical treatment in the Department of Neurosurgery a...
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[Lin Wei1, Jiang Xian2, Li Peng3, Xu Xinke1, Song Ye1]
[Absract] Objective
Intraventricular hemorrhage (IVH) triggers a vigorous neuroinflammatory cascade of inducing secondary white-matter injury and long-term neurodevelopmental impairment.Current managements remain largely supportive-primarily cerebrospinal fluid diversion for post-hemorrhagic hydrocephalus-and neither interrupts post-hemorrhagic inflammatory cascade nor promotes neural repair.In recent years,stem cells and their extracellular vesicles (EVs) have emerged as promising disease-modif...
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[Zhu Yu1,2, Chen Xiaotian3, Ye Ming2, Chen Gang2, Zhang Huifeng2, Shan Yaping1,2, Mi Yaping1,2]
[Absract] Objective
Objective To explore the guiding value of early postoperative inflammatory marker changes for antibiotic use after surgery for congenital heart disease (CHD),and to provide evidence for postoperative anti-infective treatment in children with CHD. Methods This was a retrospective cohort study included 806 children who underwent surgery for CHD and were admitted to the Cardiac Care Unit of the Children¡¯s Hospital of Fudan University between January 1,2021 and ...
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[Li Jie, Wang Yanze, Du Guoqiang, Wu Rongde, Liu Wei]
[Absract] Objective
Objective To explore the risk factors associated with urethral obstruction after tubularized incised plate urethroplasty (TIP) for hypospadias. Methods This was a retrospective case-control study.Clinical data of 253 children with hypospadias who underwent primary TIP surgery in the Department of Pediatric Urology,Shandong Provincial Hospital Affiliated to Shandong First Medical University between January 2019 and December 2022 were collected.The data includ...
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[Feng Dan1, Li Zheng2]
[Absract] Objective
Objective To explore the clinical characteristics of gastrointestinal lymphoma (GIL) in children with intussusception so as to boost the levels of its diagnosis and treatment. Methods The relevant clinical data were retrospectively reviewed for 33 GIL children with intussusception operated from March 31,2009 to July 31,2023.Follow-ups were conducted until February 2025.General profiles (gender,onset age & duration of disease),laboratory parameters,imagin...
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[Guo Hui, Zhang Yawei, Guo Xiang, Wang Jun, Ma Hui, Cheng Yintao, Chen Haitao]
[Absract] Objective
Objective To explore the clinical value of intraperitoneal fixation of peritoneal dialysis (PD) catheters during laparoscopic PD catheter insertion in children,and to evaluate the impact of this technique on the safety of early initiation of dialysis in pediatric patients. Methods This was a retrospective cohort study including 57 children who underwent laparoscopic peritoneal dialysis catheter insertion at Wuhan Children¡¯s Hospital.According to the surgical...
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[Jiang Yi, Yang Chao]
[Absract] Objective
Objective To explore the clinical characteristics,pathological features and treatments of epithelioid inflammatory myofibroblastic sarcoma(EIMS) in children. Methods From March 2013 to March 2022,the relevant clinical data were retrospectively reviewed for 7 children with diagnosed pathologically EIMS at Children¡¯s Hospital of Chongqing Medical University.Demographic profiles,clinical manifestations,laboratory measurements,treatments and outcomes were record...
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[Zheng Hongru, Wang Zhifen, Ma Junxing, Tian Ge, Wang Haoqi, Jia Wei, Liu Jinzhu]
[Absract] Objective
Objective To investigate the effects of different depths of sedation on the quantium nociceptive index (qNOX) and quantium consciousness index (qCON) during total intravenous anesthesia (TIVA) in children,and to evaluate the feasibility of regulating anesthetic maintenance based on qNOX/qCON monitoring. Methods This prospective randomized controlled trial included 150 pediatric patients who underwent elective tonsillar and adenoid radiofrequency ablation at ...
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[Liu Guoliang, Wang Fang, Zhang Jianmin, Li lijing, Li Shanshan, Wang Xiaoxue]
[Absract] Objective
Objective To explore the impact of the sideness of one-lung ventilation (OLV) (left vs right) on postoperative complications in pediatric thoracoscopy under regional cerebral oxygen saturation (rScO2) monitoring. Methods A retrospective analysis was conducted for the relevant clinical data of 100 children undergoing thoracoscopy under OLV with bilateral rScO2 monitoring between January 2022 and December 2022.Both standard and continuous...
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[Xin Liyuan, Zhang Jinshan]
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[Ding Zhili1, Hong Yaqiang1, Zhou Jinjin2, Zhuang Wenjun1]
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[Xia Jiejun, Liu Zhenyin]
[Absract] Objective
With unique etiopathogenetic mechanisms distinct from adult populations,pediatric portal hypertension is characterized by a predominance of prehepatic portal hypertension,such as cavernous transformation of portal vein.This divergence mandates forming specialized interventional approaches.Recent advances have highlighted the pivotal role of endovascular therapies:Wedged hepatic venography,a gold standard for assessing Rex recessus patency,guides candidacy for Meso-Rex bypass ...
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[Sun Zaiao1, Li Zhihui2, An Zongjian2, Xu Weili2, Gao Fei2, Sun Yong2]
[Absract] Objective
As a congenital condition characterized by a premature fusion of one or more cranial sutures,craniosynostosis disrupts normal skull and brain development.It results in elevated intracranial pressure,various cranial deformities and potential neurodevelopmental delays.Surgical intervention remains a primary treatment.This review focused upon the latest surgical approaches for craniosynostosis,aiming to provide a framework for future research directions.
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