Yang Yong,Zhou Jing,Shi Cuicui,et al.Comparing inhibitory effects between dexmedetomidine and midazolam on emergence agitation induced by intravenousinhalation combined anesthesia in children.[J].Journal of Clinical Pediatric Surgery,,17():547-551.
Comparing inhibitory effects between dexmedetomidine and midazolam on emergence agitation induced by intravenousinhalation combined anesthesia in children.
Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R]
volume:
第17卷
Number:
2018 07
Page:
547-551
Column:
论著
Date of publication:
2018-07-28
- Keywords:
- Dexmedetomidine; Midazolam; Intracenous Inhalational Anesthesia; Awakening Periodagitation
- Document code:
- A
- Abstract:
- ObjectiveTo observe the roles of dexmedetomidine and midazolam on emergence agitation after pediatric intravenousinhalation combined anesthesia.MethodsA total of 108 children aged 1~4 years undergoing laparoscopic highligation of hernia sac were selected and randomly divided into group A（dexmedetomidine),group B (midazolam) and group C（normal saline）(n=36 each).All patients were induced and maintained by general anesthesia of sevoflurane.Age,height,weight,body mass index (BMI),ASA grade and hemodynamic data before and after drug dosing were compared.Also the times of operation,anesthesia and recovery and the effect of drugs on emergence agitation after anesthesia were analyzed.ResultsNo significant differences existed in age,height,weight,BMI or ASA classification among three groups (P>0.05).There were fluctuations in SBP,DBP,HR and SpO2 among three groups,yet there were no significant differences (P>0.05).No significant differences existed in times of operation,anesthesia and postanaesthetic among three groups (P>0.05).The incidences of agitation in group A were lower than those in group C at T1,T2,T3 and T4 and the differences were statistically significant (P<0.05).No significant differences existed between groups A and C at T0 and T5 (P＞0.05) and groups A and B at various timepoints (P>0.05).ConclusionThe effect of dexmedetomidine is better than that of midazolam on emergence agitation induced by intravenousinhalation combined anesthesia.
Last Update:
2018-07-24