Yan Jiayu,Wang Kexin,Chen Yajun.Long-term outcomes of Soave procedure for Hischspung’s disease: analysis of 55 cases with over 10 years of follow-up[J].Journal of Clinical Pediatric Surgery,,():430-435.[doi:10.3760/cma.j.cn101785-20260211-00066]
Long-term outcomes of Soave procedure for Hischspung’s disease: analysis of 55 cases with over 10 years of follow-up
- Keywords:
- Hirschsprung Disease; Prognosis; Root Cause Analysis; Surgical Procedures; Operative; Child
- Abstract:
- Objective Tosummarize the long-term outcomes of the Soave procedure for Hirschsprung’s disease (HD) and to analyze potential factors affecting long-term prognosis.Methods A retrospective study was conducted on 91 children with HD who underwent the Soave procedure performed by the same surgical team at Beijing Children’s Hospital,Capital Medical University,between January 2011 and December 2015.Telephone follow-up was performed in January 2026,and all patients had postoperative follow-up of more than 10 years.Follow-up data included growth and development (height and weight) and bowel function assessed using the Rintala scoring system (maximum score:20).Results Among the 91 patients,73 were male and 18 were female.The distribution of pathological types was as follows:short-segment HD in 25 cases (25/91,27.5%),classic-segment HD in 55 cases (55/91,60.4%),long-segment HD in 8 cases (8/91,8.8%),and total colonic HD in 3 cases (3/91,3.3%).The median age at surgery was 1.3 (0.7,2.9) years.A total of 55 (55/91,60.4%) patients were successfully followed up,with a median follow-up of 12.7 (11.0,13.8) years and a follow-up age of 14.7 (13.4,16.0) years.Among these patients,52 (94.5%) and 53 (96.4%) had age-appropriate height and BMI within the normal range,respectively.The Rintala score was 20.0(19.0,20.0).There was a significant difference in the length of resected bowel among different pathological types (short-segment,classic-segment,and long-segment HD) (P<0.001).However,no significant differences were observed in long-term growth or bowel function among the groups (P>0.05).Restricted cubic spline analysis demonstrated a significant overall association between the length of resected bowel and Rintala score (P=0.0038),with a noticeable decline in Rintala score when the resected length exceeded 40 cm.Conclusion The Soave procedure provides satisfactory long-term outcomes in children with HD.A longer length of resected bowel may be a major factor associated with poor long-term bowel function.
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Memo
收稿日期:2026-2-11。
通讯作者:陈亚军,Email:chenyajunmd@aliyun.com