Zhang Jinwei,Wu Shuihua,Yuan Liping,et al.Age dependence and stratification characteristics of FOHR in children with hydrocephalus[J].Journal of Clinical Pediatric Surgery,,():360-364.[doi:10.3760/cma.j.cn101785-202510005]
Age dependence and stratification characteristics of FOHR in children with hydrocephalus
- Abstract:
- Objective To evaluate the age dependence of frontal occipital horn ratio (FOHR) in children with hydrocephalus and compare FOHR with Evans index (EI) in parallel.The distribution characteristics of FOHR under different etiologies,anatomical and physiological types and age stratification were explored to provide rationales for clinical quantitative evaluation.Methods A retrospective analysis was conducted for the relevant clinical data of 223 children with hydrocephalus admitted into Hunan Children’s Hospital from August 2017 to August 2025.They were assigned into groups based upon the causes (hemorrhage related/structural obstruction/acquired injury/inflammation) and anatomical type (communicating/non communicating/mixed).Spearman’s correlation,Kruskal Wallis test and age stratification analysis were employed.And sensitivity analysis was utilized for verifying the robustness of the conclusions.Results The results showed that patient age was 6(3,19.5) month with a FOHR of 0.559 (0.493,0.615) and an EI of 0.506 (0.418,0.588); FOHR was correlated moderately negatively with age (ρ=-0.337,P<0.001) and highly positively with EI (ρ=0.762,P<0.001); No statistically significant difference existed in the distribution of FOHR among different etiologies/types of groups (P>0.05).And the proportions of mild,moderate and severe FOHR were 28.3%,40.4% and 31.4%,respectively.Conclusions FOHR has significant age dependence and high consistency with EI quantification,making it suitable for full age follow-ups of children with hydrocephalus; Clinical interpretation should be based upon age and symptoms,with mutual confirmation of EI.Different etiologies/types should raise a high alert for the risk of severe ventricular dilation.
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Memo
收稿日期:2025-10-8。
基金项目:湖南省自然科学基金资助项目(2025JJ50682);湖南省卫生健康科研课题(20255490)
通讯作者:吴水华,Email:292454021@qq.com