Chen Ming,He Min,Wu Xuan,et al.Application value of Trapdoor surgical approach for pediatric neuroblastoma at cervicothoracic junction[J].Journal of Clinical Pediatric Surgery,,():310-315.[doi:10.3760/cma.j.cn101785-20260309-00101]
Application value of Trapdoor surgical approach for pediatric neuroblastoma at cervicothoracic junction
- Keywords:
- Neuroblastoma; Cervicothoracic Junction Tumor; Surgical Procedure; Trapdoor Surgical Approach; Children; Treatment Outcome
- Abstract:
- Objective To evaluate the technical essentials,safety and clinical application value of Trapdoor surgical approach for neuroblastoma at cervicothoracic junction in children.Methods From January 2018 to December 2025,the relevant clinicopathological data were retrospectively reviewed for 72 children with neuroblastoma at cervicothoracic junction operated via a Trapdoor approach.Surgical-related parameters and postoperative complications were recorded.And the follow-up data of survival outcomes were gathered through outpatient and telephone follow-ups.Results There were 23 boys (31.9%) and 49 girls (68.1%) with an age range from 6 months and 18 days to 10 years and 9 months.All operations were successfully completed with gross total resection.Average operative duration was (4.77±2.20) hours and intraoperative blood loss (104.11±131.20) ml.Median duration of mediastinal negative pressure drainage tubing was (7.40±2.72) day and postoperative hospital stay (10.69±5.48) day.Postoperative complications occurred (17/72,23.6%),primarily including hoarseness,pneumonia and atelectasis.During follow-ups,61 cases survived while 13 cases (13/72,18.1%) experienced disease progression or recurrence (7 cases at surgical site and 6 cases at non-surgical sites).Among 11 deaths (11/72,15.3%),the causes were disease progression (n=8) and severe infections from hemotherapy-induced severe bone marrow suppression (n=3).No death was caused by surgical complications.Conclusions For neuroblastoma at cervicothoracic junction in children,Trapdoor approach achieves a high gross total resection rate and demonstrates excellent short-term safety.Its long-term prognosis is generally favorable.However,complications remain frequent.Enhanced perioperative meticulous management and postoperative follow-ups are essential for improving long-term survival outcomes in children.
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Memo
收稿日期:2026-3-15。
基金项目:国家自然科学基金委面上项目(32270853);浙江省"尖兵领雁+X"科技计划项目(2025C01106);浙江省"尖兵""领雁"研发攻关计划项目(2024C03181)
通讯作者:王金湖,Email:wjh@zju.edu.cn