Liu Jilan,Liu Haiyan.Research advances in Klippel-Trenaunay syndrome in children[J].Journal of Clinical Pediatric Surgery,2025,(03):292-295.[doi:10.3760/cma.j.cn101785-202111013-017]
Research advances in Klippel-Trenaunay syndrome in children
- Keywords:
- Klippel-Trenaunay Syndrome; Venous Malformations; Management; Lymphatic Malformations; PIK3CA Gene
- Abstract:
- Klippel Trenaunay syndrome (KTS) is an overgrowth syndrome characterized by capillary malformations,venous malformations,extremity hypertrophy and with or without lymphatic malformations.It frequently occurs in neonates,infants and toddlers.Its etiology and pathogenesis have been associated with mutations in somatic PIK3CA gene.Its clinical manifestations are diverse and affect different organ systems.Currently there is no cure and conservative measures are applied.The major goals are early diagnosis,early intervention,reducing complications,promoting healthy development and improving quality-of-life.
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Memo
收稿日期:2021-11-7。
基金项目:山东省自然科学基金面上项目(ZR2020MH144)
通讯作者:刘海燕,Email:haiyan0326@163.com