Lan Yuru,Zhou Jiangyuan,Qiu Tong,et al.Advances in research on the treatment of complicated vascular diseases with sirolimus[J].Journal of Clinical Pediatric Surgery,,():693-696.[doi:10.3760/cma.j.cn101785-202202017-017]
Advances in research on the treatment of complicated vascular diseases with sirolimus
- Keywords:
- Complicated Vascular Anomalies; Sirolimus; Mammalian Target of Rapamycin; Surgical Procedures; Operative; Child
- Abstract:
- Vascular anomalies are a group of diseases originating from abnormal blood vessels and/or lymphatic vessels,mostly benign or borderline lesions.There are various treatment methods for vascular anomalies,but traditional treatments may be less effective for complicated/refractory vascular anomalies that involve multiple organs or systems,causing severe functional impairment or even life-threatening conditions.Sirolimus,a mammalian target of rapamycin inhibitor,has been found in recent studies to be effective for some complicated vascular anomalies.This article reviews the advances in research on the treatment of complicated vascular anomalies with sirolimus.
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Memo
收稿日期:2022-2-7。
基金项目:国家自然科学基金项目(82273556);四川省科技厅重点研发项目(2022YFS0233、2022YFS0225);四川大学从0到1创新研究项目(2022SCUH0033);四川大学医学+信息中心交叉学科建设开放项目(YGJC004);四川大学华西医院学科卓越发展1·3·5工程临床研究孵化项目(2019HXFH056、2020HXFH048);四川大学华西医院学科卓越发展1·3·5工程交叉学科创新项目(ZYJC21060)
通讯作者:吉毅,Email: