Fang Wenjuan,Chen Pengyu,Liu Xiaodong,et al.Risk factors for postoperative urinary tract infections in children with primary obstructive megaureter[J].Journal of Clinical Pediatric Surgery,,():341-347.[doi:10.3760/cma.j.cn101785-202403060-008]
Risk factors for postoperative urinary tract infections in children with primary obstructive megaureter
- Keywords:
- Primary Obstructive Megaureter; Ureteral Obstruction; Urinary Tract Infections; Risk Factors; Child
- Abstract:
- Objective To explore the risk factors for postoperative urinary tract infections (UTIs) in children of primary obstructive megaureter (POM). Methods From January 2015 to February 2023,retrospective analysis was performed for the relevant clinical data of 146 POM children.There were 97 boys and 49 girls with a median age of 23(1-17) month.The involved side was left (n=89),right (n=40) and bilateral (n=17).According to the results of postoperative urinary culture,they were assigned into two groups of infected (n=35) and non-infected (n=111).Operative duration,surgical approach,severity of hydronephrosis,ureteral width,preoperative hematological parameters,leucocyte count of preoperative urine routine,postoperative urinary routine/culture,double J tubing or not,urinary catheterization and bladder fistulas were recorded.Statistical analysis was performed for risk factors for postoperative UTIs. Results The results of univariate Logistic regression analysis indicated that age ≤1 year,leucocyte count of preoperative urine routine >5/HPF and severity of hydronephrosis >3 were risk factors for postoperative UTIs (P<0.05).The results of multivariate Logistic regression analysis revealed that the risk of postoperative UTIs in children aged ≤1 year was 3.462 folds higher than that in those aged >1 year (OR=3.462,95%CI:1.245-9.629,P=0.017).The risk of postoperative UTIs in children with leucocyte count of preoperative urine routine >5/HPF was 5.451 folds higher than that those with leucocyte count of preoperative urine routine ≤5/HPF (OR=5.451,95%CI:2.227-13.045,P<0.001).The risk of postoperative UTIs in children with hydronephrosis >grade Ⅲ was 5.473 folds higher than that in those with hydronephrosis ≤ grade Ⅲ(OR=5.473,95%CI:1.135-26.390,P=0.034). Conclusions Young POM children with leucocyte count of preoperative urine routine >5/HPF are more prone to postoperative UTIs.
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Memo
收稿日期:2023-04-13。
基金项目:国家自然科学基金委联合基金项目 (U1904208); 深圳市医学重点学科(2020—2024)(SZXK035)
通讯作者:李守林,Email:lishoulinsz@126.com