Liu Denghui,Li Ming,Tang Xianglian,et al.Diagnosis and treatment of inflammatory myofibroblastic tumor of gastrointestinal tract in children[J].Journal of Clinical Pediatric Surgery,,():178-183.[doi:10.3760/cma.j.cn101785-202308019-015]
Diagnosis and treatment of inflammatory myofibroblastic tumor of gastrointestinal tract in children
- Keywords:
- Neoplasms; Muscle Tissue; Gastrointestinal Neoplasms; Inflammation; Diagnosis; Therapy; Prognosis; Child
- Abstract:
- Objective To summarize the clinical characteristics and treatment experience of gastrointestinal inflammatory myofibroblastic tumor (IMT) in children.Methods From January 2010 to December 2021,retrospective analysis was performed for the relevant clinical data of 11 children of abdominal gastrointestinal IMT.Clinical manifestations,radiographic features,pathological examinations,surgical approaches and follow-up results were recorded.And the related literatures of pediatric abdominal inflammatory myofibroblastic tumors were retrieved.Results There were 7 boys and 4 girls with a median onset age of 56(8-180) months.The major symptoms were abdominal pain,vomiting,fever,bloody stool and abdominal lump.Total resection (n=10) was performed and postoperative chemotherapy (n=1) offered.And one child underwent biopsy plus postoperative chemotherapy.The follow-up period was (6-60) months until December 2022.Nine children were cured and 2 cases survived with tumors.One child recurred at 2 years post-operation.Conclusions The incidence of gastrointestinal IMT in children is rare.Surgery is a preferred option.Proper managements of recurrent and refractory IMT require extensive experiences and further researches.
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Memo
收稿日期:2023-8-16。
基金项目:湖南省卫生健康委科研计划课题(202104081314);湖南省自然科学基金-面上项目(2023JJ30323)
通讯作者:李勇,Email:liyongpuwaike@163.com