Li Zhiyi,Wang Jingyi,Gu Shuo.Current status of diagnosing and treating craniosynostosis and future research directions[J].Journal of Clinical Pediatric Surgery,,():101-108.[doi:10.3760/cma.j.cn101785-202401007-001]
Current status of diagnosing and treating craniosynostosis and future research directions
- Keywords:
- Craniosynostoses; Diagnosis; Therapy; Child
- Abstract:
- Craniosynostosis is a congenital condition characterized by a premature fusion of one or more bone sutures of skull.Diagnosis is mostly dependent upon three-dimensional computed tomography (CT),together with such new diagnostic modalities as "black bone" magnetic resonance imaging (MRI) and three-dimensional photography technology.Craniosynostosis usually requires surgical correction to allow for skull and brain to grow.Specific treatment options depend upon its clinical types and severity.Commonly used surgical approaches include endoscopic strip craniectomy,free-floating bone flap craniotomy and cranial distraction.Furthermore,digital simulation,surgical navigation and augmented reality (AR) are also widely applied.With rapid advancements of these technologies,future researches and developments shall evolve towards more precise intrauterine ultrasonic diagnostics,artificial intelligence prediction,genetic therapy and regenerative medicine.
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Memo
收稿日期:2024-1-3。
基金项目:2022年度国家自然科学基金项目(82260251);2022年度国家重点研发计划项目(2022YFC2305003);2022年海南省重点研发项目(ZDYF2022SHFZ292)
通讯作者:顾硕,Email:gushuo007@163.com