Liu Baihui,Xie Lulu,Yao Wei,et al.Application of associating liver partition and portal vein ligation during two-stage hepatectomy for massive hepatoblastoma[J].Journal of Clinical Pediatric Surgery,,22():1119-1123.[doi:10.3760/cma.j.cn101785-202309028-005]
Application of associating liver partition and portal vein ligation during two-stage hepatectomy for massive hepatoblastoma
- Keywords:
- Hepatoblastoma; Portal Vein; Surgery; Hepatectomy; Treatment Outcome; Child
- Abstract:
- Objective To explore the efficacy and safety of associating liver partition and portal vein ligation during two-stage hepatectomy (ALPPS) for massive hepatoblastoma.Methods The relevant clinical data were reviewed retrospectively for 4 children with hepatoblastoma undergoing ALPPS between July 2016 and February 2020.Results There were 1 boy and 3 girls with an average age of 39.5 months).ALPPS was successful.Mean future liver remnant of total liver volume (FLR/TLV) pre-intervention was (12-35.1)% and (16.3-85.2)% before stage Ⅱ resection.The average operation duration and blood loss for stages Ⅰ and Ⅱ were 286 min,150 mL and 127 min,112 mL respectively.No postoperative mortality occurred.One child underwent laparotomy and hepatic duct jejunum Roux-Y anastomosis due to obstructive jaundice after stage Ⅱ resection.During a postoperative follow-up period of (4-14) months,there were tumor-free survival (n=2),lung metastasis during chemotherapy after ALPPS (n=1) and right bone Ewing’s sarcoma (n=1).Conclusions ALPPS is both efficacious and safe for children with massive hepatoblastoma having insufficient residual liver volume for complete resection.However,more confirmative data should be required and clinical indications of ALPPS further verified in future studies.
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Memo
收稿日期:2023-9-16。
基金项目:上海市临床重点专科(shslczdzk05703);唐仲英基金会(ZSBK0070);上海市抗癌协会"雏鹰"计划(SACA—CY22C14)
通讯作者:董岿然,Email:kuirand@hotmail.com