Liu Yakai,Si Feng,Wang Songyang,et al.Clinical characteristics and related factors of emotional and behavioral problems in children with family primary nocturnal enuresis[J].Journal of Clinical Pediatric Surgery,,22():112-117.[doi:10.3760/cma.j.cn101785-202211028-003]
Clinical characteristics and related factors of emotional and behavioral problems in children with family primary nocturnal enuresis
- Keywords:
- Enuresis; Physiopathology; Enuresis; Psychology; Child Behavior; Diurnal Enuresis; Nocturnal Enuresis; Root Cause Analysis
- Abstract:
- Objective To explore the clinical characteristics and related factors of emotional and behavioral abnormality in children with family primary nocturnal enuresis(FPNE).Methods From September 2021 to September 2022,clinical data were collected from 306 children with primary nocturnal enuresis at our enuresis clinic.General information questionnaire,strengths and difficulties questionnaire and Pediatric Sleep Questionnaire(PSQ).Children with PNE were divided into family primary nocturnal enuresis group(FPNE group,n=45)and sporadic primary nocturnal enuresis group(SPNE group,n=261)according to whether family members of the third generation were involved.The clinical characteristics,emotional and behavioral changes of FPNE group were analyzed.Results The incidences of severe NE,non-monosymptomatic nocturnal enuresis(NMNE),abnormal stool and nocturnal micturition ≥ twice in FPNE group were(68%,75%,48% and 42% respectively)significantly higher than sporadic enuresis group(SPNE group)(57%,47%,24% and 11% respectively).The difference was statistically significant(P<0.05).The number of enuresis children aged 13-16 years was 44.4%(20/45)in FPNE group and it was significantly higher than 19.2%(50/261)in SPNE group.The difference was statistically significant(P<0.05).In FPNE group,46.7%(21/45)children were autosomal dominant,33.3%(15/45)children were autosomal stealth inheritance and 20.0%(9/45)children showed polygenic inheritance.The total scores of emotional symptoms、hyperactivity symptoms and difficulties in FPNE group were higher than those in SPNE group.The difference is statistically significant(P<0.05).No significant inter-group difference existed in scores of conduct problems,peer communication or society(P>0.05).Logistic regression analysis indicated that age,poor academic performance and high total score of PSQ were the influencing factors of emotional symptoms in FPNE group.Poor academic performance,abnormal stool,bladder dysfunction and high total score of PSQ were the influencing factors of hyperactivity symptoms in FPNE children.Conclusion There are many ways of inheritance of FPNE,among which autosomal dominant inheritance is the most common,the incidence of emotional symptoms and hyperactive symptoms is high,and clinical symptoms are more serious,the risk of frequent and urgent urination is higher,and it is not easy to cure with age.
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Memo
收稿日期:2022-11-13。
基金项目:国家自然科学基金(U1904208)
通讯作者:文建国,Email:wenjg@hotmail.com