Yang Guozhu,Yuan Miao,He Taozhen,et al.Review of single-center experience for surgical treatment of bronchiectasis in children[J].Journal of Clinical Pediatric Surgery,,21():1174-1178.[doi:10.3760/cma.j.cn101785-202204028-014]
Review of single-center experience for surgical treatment of bronchiectasis in children
- Keywords:
- Bronchiectasis; Surgical Procedures; Operative; Pathology; Surgical; Child
- Abstract:
- Objective To summarize the surgical experiences of bronchiectasis with pneumonectomy in children.Methods From January 2017 to December 2020,retrospective review was conducted for clinical data of children with bronchiectasis undergoing pneumonectomy at West China Hospital.There were 7 boys and 6 girls with an age range of(15-156)months.A definite diagnosed was made with high-resolution computed tomography(HRCT)and postoperative histopathology.Results Preoperative HRCT revealed marked restricted pulmonary bronchodilation with tube wall thickening partly due to foreign bodies or recurrent infection progression to bronchodilation formation(irreversible period).The procedures were lobectomy(n=11)or segsectomy(n=2).The major causes were congenital lung malformations(n=4),foreign body(n=5),pulmonary infection(n=1)and unknown(n=3).Postoperative complications included subcutaneous emphysema(n=4,30.8%),ipsilateral or contralateral lung infection(n=2,15.4%),atelectasis(n=1,7.7%)and wound infection(n=1,7.7%).Cure was achieved after conservative treatments of wound debridement,antibiotics,atomization expectorant,turnaround,back-patting and postural drainage.The outpatient follow-up period was 1 to 5 years.All clinical symptoms and quality-of-life improved significantly post-operation.Re-examination of chest HRCT hinted at an excellent recovery and there was no recurrence during follow-ups.Conclusion Congenital lung malformation,foreign body inhalation and end-stage lung infection are three major surgical indications of bronchiectasis in children.Bronchiectasis caused by various causes should be treated according to their corresponding clinical characteristics.
References:
[1] Barker AF.Bronchiectasis[J].N Engl J Med,2002,346(18):1383-1393.DOI:10.1056/NEJMra012519.
[2] Kumar A,Lodha R,Kumar P,et al.Non-cystic fibrosis bronchiectasis in children:clinical profile,etiology and outcome[J].Indian Pediatr,2015,52(1):35-37.DOI:10.1007/s13312-015-0563-8.
[3] Brower KS,Del Vecchio MT,Aronoff SC.The etiologies of non-CF bronchiectasis in childhood:a systematic review of 989 subjects[J].BMC Pediatr,2014,14:4.DOI:10.1186/s12887-014-0299-y.
[4] 中华医学会儿科学分会呼吸学组疑难少见病协作组,国家呼吸系统疾病临床医学研究中心,《中华实用儿科临床杂志》编辑委员会.儿童支气管扩张症诊断与治疗专家共识[J].中华实用儿科临床杂志,2018,33(1):21-27.DOI:10.3760/cma.j.issn.2095-428X.2018.01.006.Collaborative Group on Difficult and Rare Diseases,Group of Respiratory Medicine,Branch of Pediatrics,Chinese Medical Association;National Clinical Medical Research Center for Respiratory Diseases;Editorial Committee of Chinese Journal of Practical Pediatrics:Expert Consensus on the Diagnosis and Treatment of Bronchiectasis in Children[J].Chin J Appl Clin Pediatr,2018,33(1):21-27.DOI:10.3760/cma.j.issn.2095-428X.2018.01.006.
[5] Otgün I,Karnak I,Tanyel FC,et al.Surgical treatment of bronchiectasis in children[J].J Pediatr Surg,2004,39(10):1532-1536.DOI:10.1016/j.jpedsurg.2004.06.009.
[6] Eastham KM,Fall AJ,Mitchell L,et al.The need to redefine non-cystic fibrosis bronchiectasis in childhood[J].Thorax,2004,59(4):324-327.DOI:10.1136/thx.2003.011577.
[7] Sahin A,Meteroglu F,Kelekci S,et al.Surgical outcome of bronchiectasis in children:long term results of 60 cases[J].Klin Padiatr,2014,226(4):233-237.DOI:10.1055/s-0034-1371852.
[8] Emiralioglu N,Dogru D,Yalcin S,et al.Impact of surgery on growth,pulmonary functions,and acute pulmonary exacerbations in children with non-cystic fibrosis bronchiectasis[J].Thorac Cardiovasc Surg,2019,67(1):58-66.DOI:10.1055/s-0037-1608922.
[9] 黄敏,赵斯君,吴雄辉,等.儿童呼吸道异物延迟诊断的相关因素分析[J].临床小儿外科杂志,2018,17(10):778-782.DOI:10.3969/j.issn.1671-6353.2018.10.012.Huang M,Zhao SJ,Wu XH,et al.Analysis of correlative factors of delayed diagnosis of respiratory foreign body in children[J].J Clin Ped Sur,2018,17(10):778-782.DOI:10.3969/j.issn.1671-6353.2018.10.012.
[10] Wu YH,Dai JT,Wang G,et al.Delayed diagnosis and surgical treatment of bronchial foreign body in children[J].J Pediatr Surg,2020,55(9):1860-1865.DOI:10.1016/j.jpedsurg.2019.10.052.
[11] 袁淼,徐畅,杨纲,等.加速康复外科在胸腔镜肺切除治疗儿童先天性肺疾病中的应用[J].中华小儿外科杂志,2019,40(9):797-800.DOI:10.3760/cma.j.issn.0253-3006.2019.09.006.Yuan M,Xu C,Yang G,et al.Application of enhanced recovery after surgery during thoracoscopic pneumonectomy for congenital lung diseases in children[J].Chin J Pediatr Surg,2019,40(9):797-800.DOI:10.3760/cma.j.issn.0253-3006.2019.09.006.
[12] Rothenberg SS,Kuenzler KA,Middlesworth W.Thoracoscopic lobectomy for severe bronchiectasis in children[J].J Laparoendosc Adv Surg Tech A,2009,19(4):555-557.DOI:10.1089/lap.2009.0093.
[13] Takahashi T,Okazaki T,Doi T,et al.Video-assisted thoracoscopic double lobectomy for bronchiectasis:a case report and literature review[J].Afr J Paediatr Surg,2013,10(3):289-291.DOI:10.4103/0189-6725.120888.
[14] 王昊,徐保平,刘秀云,等.儿童支气管扩张症172例临床研究[J].中国实用儿科杂志,2014,29(12):936-939.DOI:10.7504/ek2014120613.Wang H,Xu BP,Liu XY,et al.Clinical trial of bronchiectasis in children:a report of 172 cases[J].Chin J Pract Pediatr,2014,29(12):936-939.DOI:10.7504/ek2014120613.
Memo
收稿日期:2022-4-9。
通讯作者:徐畅,Email:xcxcxc52229081@163.com