Liu Pei,Yang Yang,Huang Lei,et al.Outcomes of event-free survival in children with Wilms tumor undergoing routine lymph node dissection[J].Journal of Clinical Pediatric Surgery,,21():1111-1115.[doi:10.3760/cma.j.cn101785-202205079-003]
Outcomes of event-free survival in children with Wilms tumor undergoing routine lymph node dissection
- Keywords:
- Wilms Tumor; Lymph Node Excision; Pathology; Prognosis; Child
- Abstract:
- Objective To evaluate the prognosis of routine lymph node dissection in Wilms tumor.Methods Retrospective review was conducted for clinicopathologic parameters of 379 children with favorable-histology Wilms tumor.Based upon the approach of lymph node yield,lymph node sampling (LNS,n=337) and lymph node dissection (LND,n=42) were assigned.Results The median lymph node yield were 3 (IQR:1-4) with 23 lymph node positive in LNS group and 12 (IQR:8-15) with 4 lymph node positive.The number of lymph node yield was statistically greater in LND group (P<0.05).Among 317 patients with a median follow-up period of 43 months (IQR:19-67 months),22 developed local recurrence or metastasis,including retroperitoneal recurrence (n=11),pelvic recurrence (n=3),hepatic metastasis (n=2),lung metastasis (n=5) and brain metastasis (n=1).There were 9 deaths.No significant inter-group difference existed in event-free survival rate (P=0.580).Conclusion The prognosis of Wilms tumor is not affected obviously by routine lymph node dissection.
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Memo
收稿日期:2022-5-25。
通讯作者:张潍平,Email:zhangwpp@163.com