Pan Wenfeng,Xie Hua,Chen Fang.Biological characteristics of anogenital distance and its clinical research advances in male genitourinary disorders[J].Journal of Clinical Pediatric Surgery,,21():684-687.[doi:10.3760/cma.j.cn101785-202012034-017]
Biological characteristics of anogenital distance and its clinical research advances in male genitourinary disorders
- Keywords:
- Anogenital Distance; Prenatal Androgen Action; Environmental Endocrine; Male Reproductive Health
- Abstract:
- The incidence of male genitourinary disorders is rising annually.It has a negative impact on male reproductive health.An interruption or an insufficient level of prenatal androgen may be one of the important reasons for this phenomenon.Anogenital distance (AGD) is not only an important indicator for sex dimorphism, but also an important biomarker for androgen exposure, environmental endocrine disruptors (EDCs) and reproductive toxicology.This review offered a brief review of biological characteristics of AGD and its clinical research advances in male genitourinary disorders.
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Memo
收稿日期:2020-12-11。
基金项目:上海市科学技术委员会科研计划项目(14411950403);上海申康医院发展中心临床三年行动计划资助(SHDC2020CR3013A)
通讯作者:陈方,Email:chenfang01@sjtu.edu.cn