Zhou Yuxiang,Liu Denghui,Wen Jiabing,et al.Clinical characteristics and risk factors for recurrent intussusception in children: A single-center retrospective study[J].Journal of Clinical Pediatric Surgery,,21():653-657.[doi:10.3760/cma.j.cn101785-202203068-011]
Clinical characteristics and risk factors for recurrent intussusception in children: A single-center retrospective study
- Keywords:
- Intussusception/ET; Intussusception/PP; Intussusception/SU; Recurrence; Enema; Risk Factors; Child; Retrospective Studies
- Abstract:
- Objective To explore the clinical characteristics and recurrence risk factors of intussusception to boost the diagnosis and treatment of recurrent intussusception in children.Methods From January 2015 to December 2019, clinical data were retrospectively reviewed for 6874 children of intussusceptions.They were divided into two groups of recurrent intussusceptions (n=1376) and non-recurrent intussusceptions (n=5498).According to the age of initial intussusception, they were assigned into 6 age groups: ≤ 1 year old, 1-2 years old, 2-3 years old, 3-4 years old, 4-5 years old and >5 years old.Clinical characteristics of recurrent intussusception were summarized, univariate analysis was performed and the inter-group differences were compared.Variables with significant differences (P<0.05) were further included into multivariate Logistic analysis for exploring the risk factors correlated with recurrent intussusception.Results The overall recurrence rate was 20.0% (1376/6874).Univariate analysis hinted at statistically significant inter-group differences in age, clinical symptoms (vomiting, abdominal pain, bloody stool/jam stool), head position, abdominal mass and complicated secondary pathological lead points (PLPs)(P<0.05).Multivariate Logistic analysis indicated that age (OR=4.431, OR value 95%CI:1.549-5.167, P<0.001), vomiting (OR=0.259, OR 95%CI:0.278-0.691, P<0.001), blood stool/jam stool (OR=0.498, OR 95%CI:0.325-0.802, P=0.003) and combined PLPs (OR=3.378, 95%CI:2.851-12.071, P<0.001) were the correlated factors of intussusception recurrence.The recurrence rate within 1 year old was the lowest (15.3%, 290/1896), operation rate was the highest (20.7%, 394/1896) and PLPs cases were the highest in group over 5 years old (9.4%, 31/330).Conclusion The younger age, the lower recurrence rate of intussusception.With advancing age, the proportion of children with PLPs of intussusception increased.Age, PLPs, vomiting and symptoms of bloody/jam stool are associated with intussusception recurrence.
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Memo
收稿日期:2022-03-22。
基金项目:国家临床重点专科建设项目-湖南省儿童医院小儿外科（湘卫医发[2022]2号）
通讯作者:刘登辉,Email:liudenghui0505@163.com