Han Jinbao,Yu Mengnan,Liu Gang,et al.A comparative study on surgical outcome of neonatal necrotizing enterocolitis between nonperforated and perforated cases[J].Journal of Clinical Pediatric Surgery,,21():530-534.[doi:10.3760/cma.j.cn101785-202007046-006]
A comparative study on surgical outcome of neonatal necrotizing enterocolitis between nonperforated and perforated cases
- Keywords:
- Enterocolitis; Necrotizing/DI; Enterocolitis; Necrotizing/SU; Intestinal Perforation; Treatment outcome; Infant; Newborn
- Abstract:
- Objective To compare the recovery of neonatal necrotizing enterocolitis (NEC) with intestinal perforation and non-perforated bowel after surgical treatment to provide references for selecting operative timing and postoperative treatments of NEC.Methods From August 2009 to August 2019, retrospective analysis was performed for 237 children with surgical NEC.They were divided into two groups of non-perforated (n=172) and perforated group (n=65).Various postoperative factors (infection status, complications, enteral & parenteral nutrition time, ICU time, ventilator use time & intestinal necrosis length) were compared between two groups.Results In non-perforation group, 124 cases were cured and 48 died (48/172, 27.9%);in perforated group, 48 cases were cured and 17 died (17/65, 26.2%).Length of necrotic bowel, postoperative parenteral nutrition time, enteral nutrition time, ventilator use time, NICU stay time and postoperative complications were compared between two groups.And the difference was statistically significant (P<0.05).Comparison of mortality between ⅢA and ⅢB groups in Bell stage (χ2=4.731, P=0.030) and the difference was statistically significant.Conclusion Compared with perforated group, nonperforated group has longer gut necrosis.And children in non-perforated group have more serious complications and have a longer recovery time post-operation.Indications for nonperforated surgical NEC need to be further verfied.
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Memo
收稿日期:2020-07-28。
基金项目:军委后勤保障部卫生局，应用基础研究项目（21JSZ18）
通讯作者:黄柳明,Email:surhlm@126.com