Lin Tulian,Wu Qiang,Peng Yanfen,et al.Risk factors of high-output stoma after enterostomy in necrotizing enterocolitis[J].Journal of Clinical Pediatric Surgery,,21():310-314.[doi:10.3760/cma.j.cn101785-202201058-003]
Risk factors of high-output stoma after enterostomy in necrotizing enterocolitis
- Keywords:
- Enterocolitis; Necrotizing/SU; Enterostomy; Diarrhea; Postoperative Complications; Risk Factors; Infant; Newborn
- Abstract:
- ObjectiveTo explore the risk factors of high-output stoma(HOS)after enterostomy in infants with necrotizing enterocolitis(NEC).MethodsFrom July 1,2017 to June 30,2021,76 neonates undergoing enterostomy due to NEC were retrospectively reviewed.They were divided into two groups of HOS(n=25)and non-HOS(n=51)according to whether or not HOS occurred after enterostomy.General demographics,intraoperative findings and prognosis of two groups were compared.Univariate and multivariate Logistic regressions were utilized for examining the risk factors of HOS after enterostomy.ResultsUnivariate analysis indicated that birth weight,gestational age,preoperative need for respiratory support,NEC stages and subtypes,corrected gestational age,operative weight and residual length of proximal enterostomy were the relevant occurring factors for postoperative HOS(P＜0.05).Logistic regression analysis showed that residual length of proximal enterostomy was an independent risk factor of HOS after enterostomy in NEC infants(OR=1.220,95%CI:1.108-1.343,P＜0.05).Receiver operating characteristic(ROC)curve was plotted with residual length of proximal enterostomy.Area under the curve was 0.926(95%CI:0.849~1.000,P＜0.05)while the sensitivity and specificity were 92% and 74%.When residual length of proximal enterostomy was 86.5 cm,the sensitivity and specificity were 84% and 96% of HOS,indicating that it was an excellent predictor for HOS in NEC infants.ConclusionHOS is prone to occur after enterostomy in NEC infants and residual length of proximal enterostomy is an independent risk factor and an excellent predictor for HOS in NEC infants after enterostomy.
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Memo
收稿日期:2022-01-29
通讯作者:钟微,Email:zhongwei@gwcmc.org