Cheng Zhen,Wu Zhouguang,Ye Yongqin.Recent advances in noninvasive diagnosis of biliary atresia in early stage[J].Journal of Clinical Pediatric Surgery,,20():785-790.[doi:10.12260/lcxewkzz.2021.08.015]
Recent advances in noninvasive diagnosis of biliary atresia in early stage
- Keywords:
- Biliary Atresia; Early Diagnosis; Noninvasiveness; Review
- CLC:
- R726.574.4;R726.1
- Abstract:
- As a common cause of neonatal obstructive jaundice, biliary atresia (BA) is characterized by inflammation and progressive fibrosis of extrahepatic or intrahepatic bile ducts. An early diagnosis may significantly improve the prognosis of children and lower the incidence of complications. Therefore an early diagnosis of BA is particularly important. Currently the gold standards for diagnosing BA are intraoperative cholangiography and liver pathological biopsy. Such a diagnostic mode is invasive and often requires the judgment of senior doctors. Thus it is imperative to seek a non-invasive and quantitative tool with high sensitivity and specificity. This review summarized the latest researches in the diagnostic efficacy of BA through stool colorimetric cards, stool, urine, blood-derived markers and imaging studies to provide rationales for clinical diagnosis and treatment.
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Memo
收稿日期:2020-07-25。
基金项目:2018年度深圳市医疗卫生三名工程（编号：SZSM201812055）
通讯作者:吴宙光,Email:guang99b3@163.com