Feng Wei,Zhao Xufeng,Cui Hualei.Advances of etiology about acute appendicitis in children[J].Journal of Clinical Pediatric Surgery,,20():592-596.[doi:10.12260/lcxewkzz.2021.06.016]
Advances of etiology about acute appendicitis in children
- Keywords:
- Appendicitis/ET; Appendicitis/SU; Child
- CLC:
- R574.61;R656.8
- Abstract:
- Acute appendicitis is a common acute abdomen in pediatric surgery.It is traditionally believed that the pathogenesis is an overgrowth of bacteria and inflammatory reactions caused by an obstruction of appendiceal cavity,resulting in edema and neutrophil infiltration in cavity,muscle wall and surrounding tissues of appendix.However,current studies have revealed that acute appendicitis in children is associated with primary infection,genetic susceptibility,diet,environment,abdominal trauma and appendiceal deformity.Understanding its etiological mechanism is conducive for selecting appropriate treatments.Early surgery is indicated for appendiceal obstruction,appendiceal deformity and trauma.Most other causes may be treated with antibiotics.This review summarized recent advances in the etiological mechanism of acute appendicitis in children for enhancing its relevant knowledge.
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Memo
收稿日期:2019-03-27;。
基金项目:天津市科技计划项目（编号：14RCGFSY00150）
通讯作者:崔华雷,Email:chlfjp@sina.com