Hu Jing,Hua Lei,Huo Lianghong,et al.Analysis of influencing factors of adequate anesthesia time ratio of closed-loop infusion of propofol in children[J].Journal of Clinical Pediatric Surgery,,20():458-463.[doi:10.12260/lcxewkzz.2021.05.012]
Analysis of influencing factors of adequate anesthesia time ratio of closed-loop infusion of propofol in children
- CLC:
- R726;R614
- Abstract:
- Objective To explore the influencing factors of adequate anesthesia time ratio (BIS40-60%) during CL-TCI infusion and adopt more rigorous monitoring for children with possible low BIS40-60%.Methods American Society of Anesthesiologists physical status Ⅰ~Ⅳ children (12-36 months,male=female=38;37-216 months,male=female=38) undergoing elective non-craniocerebral general anesthesia were included.Propofol was delivered through a closed-loop anesthesia delivery system.The target bispectral index (BIS) value was set at 50 during maintenance anesthesia.BIS40-60%,gender,body temperature,age,BMI,ASA grading,anesthesia duration and blood loss were recorded.Results Both ASA grade and age affected BIS 40-60% and the impact of ASA grade was more obvious.The regression equation was 71.72+0.15*month-6.82*ASA,R2=0.53.And 17 month was the age split value in month age decision tree.Conclusion As for propofol CL-TCI technology,preoperative ASA grade and young age are the risk factors leading to a 40-60% reduction in BIS and ASA grade has a greater impact on the stability of the system.For ASA Ⅲ magnitude or age 17 months or under,children should be closely observed for intraoperative sedation depth and regulation.
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Memo
收稿日期:2020-10-24。
基金项目:吴阶平医学基金会临床科研专项资助基金（编号：320.6750.19089-102）
通讯作者:张建敏:Email:zjm428@sina.com