Li Yi,Song Hongcheng,He Yuzhu,et al.Short-term changes in renal function after operations for congenital ureteropelvic junction obstruction[J].Journal of Clinical Pediatric Surgery,,20():312-318.[doi:10.12260/lcxewkzz.2021.04.003]
Short-term changes in renal function after operations for congenital ureteropelvic junction obstruction
- CLC:
- R726.9;R692.2;R693
- Abstract:
- Objective To evaluate the short-term postoperative changes of differential renal function(DRF) in children with unilateral renal ureteropelvic junction obstruction(UPJO) before and after surgery.Methods From March 2019 to October 2019, a total of 50 children undergoing unilateral UPJO pyeloplasty were analyzed.There were 37 boys and 13 girls.According to the preoperative DRF, they were divided into three groups of preoperative DRF reduction(DRF<40%), preoperative DRF normal(40% < DRF < 55%) and preoperative DRF supernormal(DRF>55%).Renal function and renal parenchymal thickness of the affected side in each group were compared before and after operation.There were postoperative improvements of DRF between groups.Results Significant differences existed in age, surgical approach and postoperative DRF among three groups(P<0.05).In preoperative DRF reduction and supernormal groups, there were statistical differences in DRF before and after surgery(P<0.05).It showed no significant change in DRF before and after operation in preoperative DRF normal group.In preoperative DRF normal group, significant differences existed in renal parenchymal thickness(P<0.05).An elevation of postoperative DRF ≥ 5% was adopted as a standard of postoperative improvement of renal function(postoperative reduction of DRF ≥ 5% as a standard for preoperative DRF supernormal group), postoperative improvement of DRF showed significant statistical differences among three groups(P<0.05).However, the level of postoperative renal function was still lower in preoperative DRF reduction group than that in preoperative DRF normal and supernormal groups(all P<0.05).Conclusion Renal function in preoperative DRF <40% group recovered markedly.However, the level of postoperative renal function was still lower in preoperative DRF reduction group than that in preoperative DRF non-reduction group.
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Memo
收稿日期:2021-01-03。
基金项目:北京市医院管理中心儿科学科协同发展中心专项经费资助（编号：XTZD20180303）
通讯作者:张潍平,Email:zhangwp59616406@126.com