Jiang Jingying,Ju Zhaoru,Sun Yinghua,et al.Application of shear wave elastography for diagnosing biliary atresia: a Meta-analysis[J].Journal of Clinical Pediatric Surgery,,20():126-132.[doi:10.12260/lcxewkzz.2021.02.005]
Application of shear wave elastography for diagnosing biliary atresia: a Meta-analysis
- CLC:
- R657.4+4 R445.1
- Abstract:
- Objective To determine the value of shear wave elastography (SWE) in the diagnosis of biliary atresia (BA) through a meta-analysis of the relevant recent researches.Methods According to the retrieval criteria,the Chinese and English database literature was searched and the articles were screened and selected.The included literature was evaluated by the QUADAS-2 scale.The relevant data were extracted and SROC curve was plotted.Results A total of 132 relevant literatures were retrieved.Based upon the eligibility criteria,7 studies were finally included for data analysis.The results showed that the area under the SROC curve of SWE for diagnosing BA was 0.90(95%CI:0.88-0.93),the combined sensitivity 81% (95%CI:72%-92%) and the combined specificity 85%(95%CI:70%-91%).Conclusion SWE is valuable for diagnosing BA.However,there is still a lack of prospective and high-quality clinical diagnostic tests.The heterogeneity of previous studies is high so that the diagnostic value of SWE should be further verified.Meanwhile the method of SWE in children remains to be further improved and standardized.
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Memo
收稿日期:2020-04-20。
基金项目:上海市重点学科（编号：2017ZZ02022）；上海市临床重点专科（编号：shslczdzk05703）；国家儿童医学中心"海聚"国际联合实验室（编号：EK1125180104）；国家儿童医学中心青年临床科学家项目（编号：EK112520180310）
通讯作者:郑珊,Email:szheng@shmu.edu.cn