Yasenjiang·Abudoula,Zhou Ling.Changes of serum inhibitor B levels in children with cryptorchidism[J].Journal of Clinical Pediatric Surgery,,20():93-97.[doi:10.12260/lcxewkzz.2021.01.018]
Changes of serum inhibitor B levels in children with cryptorchidism
- Keywords:
- Inhibins; Cryptorchidism; Testis
- CLC:
- R726.9;R697+.22
- Abstract:
- As the most common type of urogenital dysplasia in males,cryptorchidism is characterized by unilateral or bilateral testes descending to scrotal process.An elevated serum level of follicle stimulating hormone (FSH) and a lower serum level of inhibin b (INH-B) concentrations are endocrine markers of abnormal testicular support cell/quulin tube function.Many studies of males with a history of cryptorchidism have hinted at the involvement of testicular support cells/perciprocal function (spermatogenesis).However,the function of Leydig cell is not affected.Thus the assessment of testicular function is mainly focused upon testicular support fineness extent of cell damage in pre-puberty adolescents with cryptorchidism.Currently inhibin B is the most effective endocrine marker for testicular support cells.And its serum level offers a safer,more convenient and indirect way of evaluating testicular function after cryptorchidism reduction and fixation.Here recent adavances of inhibitor B and its diagnostic significance were summarized for children with cryptorchidism.
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Memo
收稿日期:2019-04-13。
基金项目:新疆维吾尔自治区自然科学基金资助项目（编号：2019D01C123），新疆医科大学研究生创新创业启动基金项目（编号：CXCY2018002），新疆维吾尔自治区人民医院科技引进创新项目（编号：20180313）
通讯作者:周玲,Email:zhouling781004@163.com