Xie Yimin,Nin Jinbo,Yao Mingmu,et al.Effect of hemorrhage of large cystic lymphatic malformation on therapeutic efficacy of sclerotherapy in children[J].Journal of Clinical Pediatric Surgery,,20():65-68.[doi:10.12260/lcxewkzz.2021.01.013]
Effect of hemorrhage of large cystic lymphatic malformation on therapeutic efficacy of sclerotherapy in children
- Keywords:
- Lymphatic Abnormalities; Sclerotherapy; Lauromacrogol; Child
- CLC:
- R729;R551.2
- Abstract:
- Objective To explore the effect of hemorrhage of large cystic lymphatic malformation on therapeutic efficacy of sclerotherapy in children.Methods Based upon tumor history,color Doppler ultrasound,magnetic resonance imaging (MRI) and puncture result,a total of 50 children of large cystic lymphatic malformation were divided into bleeding group (n=22) and non-bleeding group (n=28).After an aspiration of cystic fluid,an injection of lauromacrogol was performed under the guidance of color Doppler ultrasound.Pressure bandage was applied for 2-3 days and the status of lumps checked after 2 weeks.The same procedure was repeated until the disappearance of lumps.After an initial sclerotherapy,size changes and treatment frequency were recorded.Lump disappearance was judged as excellent,50% or more reduction effective and <50% reduction ineffective.Results After an initial treatment,the outcomes of bleeding group were excellent (n=4),effective (n=9) and ineffective (n=9).The effective rate was 59.09%;the outcomes of non-bleeding group were excellent (n=10),effective (n=14) and ineffective (n=4).The effective rate was 85.71%.There were significant inter-group differences (χ2=4.539,P<0.05).Finally all lumps disappeared with a total effective rate of 100%.The average treatment frequency was (3.55±1.26) in bleeding group versus (2.57±1.35) in non-bleeding group.There were significant inter-group differences(t=2.611,P<0.05).Conclusion Hemorrhage of large cystic lymphatic malformation may reduce the therapeutic effect of sclerotherapy in children.However,in the end lumps were totally disappeared,but the number of treatments was increased.
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Memo
收稿日期:2018-05-24。
基金项目:重庆市卫生计生委医学科研项目（编号：2016MSXM120）
通讯作者:宁金波,Email:xym0309@163.com