Wang Xun,Xiao Zhenghui,Chen Zhi,et al.Follow-up study of ventricular preexcitation dilated cardiomyopathy in children[J].Journal of Clinical Pediatric Surgery,,19():1123-1129.[doi:10.3969/j.issn.1671-6353.2020.12.012]
Follow-up study of ventricular preexcitation dilated cardiomyopathy in children
- Keywords:
- Cardiomyopathy; Dilated; Pre-Excitation Syndromes; Catheter Ablation; Follow-up Studies; Child
- CLC:
- R726.1;R542.2
- Abstract:
- Objective To explore the clinical manifestations,treatments and prognosis of ventricular preexcitation dilated cardiomyopathy (DCM) in children.Methods Clinical manifestations,electrophysiological findings and echocardiographic results were retrospectively reviewed for 5 children of ventricular preexcitation DCM at Hunan Children’s Hospital from September 2016 to June 2019.Results There were 3 boys and 2 girls with an age of initial examination of (0.5-6) years.The follow-up period was (1-12) months after catheter ablation.Electrocardiogram revealed type B ventricular preexcitation while ultrasound hinted at left ventricle (LV) dilation,LV dysfunction and incoordination movement between posterior wall of left ventricle and basal segments of ventricular septum.Asynchronization of left ventricular wall motion was detected by speckle tracing.The locations of accessory pathway were right-sided anteroseptum and free wall.Electrocardiogram indicated the presence of sinus rhythm and delta wave disappeared completely in 4 children.Echocardiograph demonstrated synchronous contraction.Left ventricular end diastolic diameter (LVEDD) gradually decreased to almost normal during follow-ups.In one child,delta wave of QRS disappeared completely and contraction regained synchrony during 6-month follow-up while LVEDD and LVEF normalized during 1-year follow-up.Conclusion Overt right-sided accessory pathways may cause DCM in anteroseptum and free wall.Asynchronous ventricular contraction is a vital mechanism of ventricular preexcitation DCM.Radiofrequency ablation therapy is indicated for ventricular preexcitation DCM with an excellent prognosis.
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Memo
收稿日期:2020-01-22。
基金项目:国家自然科学基金（编号：81500041）；湖南省重点实验室平台项目（编号：2018TP1028）；湖南省临床医疗技术创新引导项目（编号：2018SK50413）
通讯作者:肖云彬,Email:xiaoyunbinrui@126.com