Hu Jiajian,Sun Jihang,Chen Yiwei,et al.Correlational research between image danger risk factor and surgical complications of retroperitoneal neuroblastoma in children[J].Journal of Clinical Pediatric Surgery,,19():903-908.[doi:10.3969/j.issn.1671-6353.2020.10.008]
Correlational research between image danger risk factor and surgical complications of retroperitoneal neuroblastoma in children
- Keywords:
- Neuroblastoma; Retroperitoneal Neoplasms; Risk Factors; Intraoperative Complications; Postoperative Complications; Child
- CLC:
- R735.4;R445;R730.6
- Abstract:
- Objective To explore the correlation and clinical significance of image defined risk factor (IDRF) with operative complications in children undergoing retroperitoneal neuroblastoma resection.Methods From June 2016 to June 2017,the clinical and imaging data were retrospectively analyzed for 68 children with retroperitoneal neuroblastoma undergoing surgical resection.IDRF was defined according to the standard of International Neuroblastoma Risk Group (INRG).The correlation between the numbers of preoperative IDRF and surgical complications was analyzed by Spearman’s correlation coefficient method.The ROC curve was plotted for analyzing the predictive value of the number of IDRFs for surgical complications.Results There were 32 boys and 36 girls with a median onset age of 33(0-148) months.The median number of preoperative IDRFs was 2(0-11).A total of 76 complications occurred in 39 children with a median number of 1(0-4) complication.Postoperative electrolyte disturbance was the most common complication (21/76).The number of operative complications was significantly correlated with the number of IDRF in each patient (r=0.713,P<0.05).And the number of IDRF was correlated with all direct operative complications (r=0.700,P<0.05) and all indirect operative complications (r=0.420,P<0.05).The area under curve in ROC was 0.894 (95%CI 0.813-0.975).The number of IDRF had a cut-off value of 2.And the values of sensitivity,specificity,positive predication and negative predication were 85.4%,85.2%,89.7% and 79.3% respectively.Conclusion IDRF is valuable for assessing surgical outcomes due to its important correlation with the occurrence of operative complications.
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Memo
收稿日期:2019-01-13。
通讯作者:王焕民,Email:wanghuanmin@bch.com.cn