Wang Pei,Feng Jiexiong.The antibiotics treatment of cholangitis Post-Kasai Portoenterostomy: A multi-center study protocol[J].Journal of Clinical Pediatric Surgery,,18():922-926.[doi:10.3969/j.issn.1671—6353.2019.11.006]
The antibiotics treatment of cholangitis Post-Kasai Portoenterostomy: A multi-center study protocol
- Keywords:
- Biliary Atresia/DT; Cholangitis; Antibiotic Prophylaxis; Multicenter Studies; Research Design
- CLC:
- R657.4+4;R575.7
- Abstract:
- Cholangitis is the most common postoperative complication of BA,and the incidence is about 60%~90%.Recurring cholangitis is an important risk factor affecting the postoperative life quality of children with BA.However,there is no unified guideline for the severity of cholangitis and the related treatment.Therefore,this study is a multi-center and prospective research,intending to clarify the antibiotics treatment of cholangitis.A total of 190 cholangitis children will be recruited and randomized into control group(n=95) and experimental group(n=95),all control groups were treated with the same antibiotics,and the experimental group were treated with different antibiotics according to the severity of cholangitis,then evaluate the cure rate 3 days and 7 days later.This multi-center prospective study may provide a reliable reference for the standardized treatment of cholangitis.
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Memo
收稿日期:2017-04-18。
基金项目:国家自然科学基金（编号：81873541）
通讯作者:冯杰雄,Email:fengjiexiong@126.com