Chen Zirong,Li Yakun,Wan Feng.Clinicopathological features of children with neurological tumors[J].Journal of Clinical Pediatric Surgery,,18():723-727.[doi:10.3969/j.issn.1671-6353.2019.09.003]
Clinicopathological features of children with neurological tumors
- Keywords:
- Nervous System Neoplasms; Pathological Conditions; Signs and Symptoms; Molecular Pathology; Prognosis; Child
- CLC:
- R726;R739.4;R739.41
- Abstract:
- Central nervous system (CNS) tumors are the most common pediatric cancers after hematological malignancies and the most common pediatric solid organ tumor.CNS tumors remain the most common cause of cancer-related mortality in children aged 0-14 years.Susceptible locations,pathologies and genetic aberrations of pediatric CNS tumors are significantly divergent from their adult counterparts.Meanwhile,they also manifest vastly different growth and imaging characteristics.Radiochemotherapy is often associated with poor outcomes.For infants and young children with highly malignant tumors,radiotherapy is not applicable.Meanwhile,the most common low-grade gliomas and other benign tumors such as craniopharyngioma,have slow progression and recurrence.Improving the quality-of-life and prognosis of pediatric CNS tumors requires more extensive multidisciplinary collaborations.
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Memo
收稿日期:2019-05-13。
通讯作者:万锋,Email:wanruiyan@hotmail.com