Sun Junjie,Shu Man,Gao Pengfei,et al.Clinical analysis of diagnosing and treating gastrointestinal stromal tumors in children[J].Journal of Clinical Pediatric Surgery,,18():707-710.[doi:10.3969/j.issn.1671-6353.2019.08.018]
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Clinical analysis of diagnosing and treating gastrointestinal stromal tumors in children

Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R] volume: 第18卷 Number: 2019 08 Page: 707-710 Column: 儿童罕见病 Date of publication: 2019-08-25
Author(s):
Sun Junjie1; 2;  Shu Man3;  Gao Pengfei1;  Jiang Hong1;  Liu Juncheng1;  Zhou Li1
1. Department of Pediatric Surgery;
2. Department of Urology Surgery, Municipal Children’s Hospital, Shenzhen 518038, China;
3. Department of Pathology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
Keywords:
Child; Gastrointestinal Stromal Tumors/DI; Gastrointestinal Stromal Tumors/TH; Wild-type
CLC:
R735.2;R735.3
DOI:
10.3969/j.issn.1671-6353.2019.08.018
Abstract:
Objective To summarize the clinical characteristics,diagnosis and treatment of gastrointestinal stromal tumors in children.Methods Three children diagnosed as gastrointestinal stromal tumors were admitted over the last five years.Retrospective analysis was performed for clinical data of 3 cases along with a review of related literature studies.Results There were 1 boy and 2 girls with a median age of 12 years.Their clinical manifestations included dizziness,fatigue,pale complexion,melena and abdominal pain.Endoscopy revealed submucosal tumor with hemorrhage and abdominal computer tomography (CT) hinted at an occupation of soft mass at the lesser gastric curvature.Surgical options were partial gastrectomy and metastatic tumor resection;All 3 cases received tyrosine kinase inhibitors post-operation.During a follow-up period of 10-48 months,1 recurrent case was re-operated while the remainder was uneventful.Conclusion Pediatric gastrointestinal stromal tumors are extremely rare and most cases belong to wild-type.Both gastroscopy and abdominal CT are helpful for reaching a definite diagnosis.Comprehensive therapy is essential and surgery remains a major treatment.

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Memo

收稿日期:2018-08-30。
通讯作者:高鹏飞,Email:gaofei.06@163.com

Last Update: 1900-01-01