Wu Shaofeng,He Rong,Sun Jie,et al.Twostaged urethroplasty with tissueengineered graft for proximal hypospadias with severe chordee.[J].Journal of Clinical Pediatric Surgery,,17():577-580.
Twostaged urethroplasty with tissueengineered graft for proximal hypospadias with severe chordee.
Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R]
volume:
第17卷
Number:
2018 08
Page:
577-580
Column:
专题讨论
Date of publication:
2018-08-28
- Document code:
- A
- Abstract:
- ObjectiveTo explore the efficacy of xenogenous grafts as substitution for urethroplasty in proximal hypospadia with severe chordee and report the feasibility and shortterm outcomes of penile straightening using tissue engineered decellularized matrix.MethodsA total of 82 patients were recruited for twostage urethroplasty between June 2011 and September 2016. Penile curvature was straightened with decellularized matrix graft for repairing tunica albuginea defects after skin degloving and urethral plate transaction. Transverse island preputial flaps were preserved for secondstage urethroplasty at least 6 months apart.ResultsAll of them with severe chordee received chromosome or SRY gene test. Ventral curvatures were corrected successfully without severe complications during the firststage reconstruction. And artificial erection was induced for confirming straightening maneuvers during the secondstage operation. The shortterm complications included urethral meatal stricture (n=6, 7.3%)，urethrocutaneous fistula (n=9, 11%) and urethral diverticulum (n=2, 2.4%). Postoperative functional and cosmetic appearances were satisfactory during the followup period.ConclusionTissueengineered matrix grafting for straightening chordee of proximal hypospadias is efficacious for select patients.
Last Update:
2018-08-21