Zuo Chao,Chen Zhi,Xiao Yunbin,et al.Therapeutic strategy and effectiveness of unconventional device application in low-weight children with long patent ductus arteriosus[J].Journal of Clinical Pediatric Surgery,,19():930-934.[doi:10.3969/j.issn.1671-6353.2020.10.013]
Therapeutic strategy and effectiveness of unconventional device application in low-weight children with long patent ductus arteriosus
- Keywords:
- Infant; Low Birth Weight; Ductus Arteriosus; Patent; Treatment Outcome
- CLC:
- R726.2;R654.3
- Abstract:
- Objective To summarize the therapeutic strategy and effectiveness of unconventional device application in low-weight children with long patent ductus arteriosus (PDA).Methods Methods From January 2017 to December 2019,clinical data of low-weight children with long PDA (diameter >3 mm) were retrospectively analyzed.They were divided into two groups of muscular ventricular septal defect (MVSD) and second-generation Amplatzer PDA.Clinical manifestations and incidence of complications were summarized.Results There were a total of 15 patients with an average age of 4(2.0-7.5) months and an average body weight of (4.85±1.15) kg.PDA closure was successfully achieved by MVSD occluder (n=9) or second-generation Amplatzer PDA occluder (n=6).Body weight was (5.32±1.17) kg in MVSD occluder group and (4.15±0.75) kg in second-generation Amplatzer PDA group respectively.And the length and diameter of PDA were (9.71±1.50) and (5.03±1.00) mm in MVSD occluder group and (8.0±0.5) and (3.67±0.82) mm in second-generation Amplatzer PDA group respectively.There were 3 cases of comorbidity with residual shunt in MVSD occluder group and comorbidities with descending aortic stenosis (n=2) and thrombocytopenia (n=5) in MVSD occluder group.Cardiothoracic ratio declined markedly (P<0.05) post-operation compared with pre-operation in MVSD occluder group (0.61±0.03 vs. 0.65±0.03) and second-generation Amplatzer PDA occluder group (0.58±0.03 vs. 0.61±0.03).Comorbidity with residual shunt (n=4) and descending aortic stenosis (n=1) occurred in second-generation Amplatzer PDA occluder group.Dislocation and shift of device or stenosis of left pulmonary was not detected. Conclusion Low-weight children with long PDA (diameter >3 mm) may be effectively treated by MVSD occluder and second-generation Amplatzer PDA occluder.The former is suitable for PDA with a diameter of >5 mm while the latter is ideal for PDA with a diameter of between 3-5mm.
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Memo
收稿日期:2020-02-06。
基金项目:湖南省卫生计生委科研计划课题项目（编号：B2019014）
通讯作者:陈智,Email:eychenzhi@163.com