Hu Jiajian,Huang Yijin,Han Jianyu,et al.Abdominal inflammatory myofibroblastic tumors in children: a clinical diagnosis and treatment review[J].Journal of Clinical Pediatric Surgery,,19():336-341.[doi:10.3969/j.issn.1671-6353.2020.04.011]
Abdominal inflammatory myofibroblastic tumors in children: a clinical diagnosis and treatment review
- Keywords:
- Neoplasms; Muscle Tissue/DI; Neoplasms; Muscle Tissue/SU; Treatment Outcome; Child
- CLC:
- R726.1;R730.269;R730.262
- Abstract:
- Objective To explore the diagnosis and treatment of abdominal inflammatory myofibroblastic tumors in children.Methods Retrospective analysis was performed for clinical data of 18 children of abdominal inflammatory myofibroblastic tumors from January 2006 to January 2018.The relevant clinical data included age at diagnosis,size of lesion,presenting symptoms,history of previous illness,radiographic findings,pathological examination and clinical outcomes.The literatures of pediatric abdominal inflammatory myofibroblastic tumors were reviewed.All 18 cases were examined preoperatively by ultrasonography,computed tomography (CT) and magnetic resonance imaging (MRI).The interventions included preoperative puncture plus chemotherapy (n=1),biopsy plus postoperative chemotherapy (n=1) and total resection (n=16).Two cases of diffuse abdominal lesions received postoperative systemic chemotherapy.Results Postoperative pathology showed that tumor cells were fusiform with inflammatory infiltrate and sometimes focal hemorrhage or vitreous degeneration was evident.One case was lost to follow-up and one case with tumor in retroperitoneal space died at 4 months post-operation.During a follow-up period of 4-29 months,the remainder had no postoperative death or complications.One survived with abdominal IMT lesions.Conclusion IMT may occur in any abdominal region with diverse symptoms.Imaging examinations aid its localization and diagnosis but it lacks specificity.Solitary lesions are cured by simple operation.For refractory cases with diffuse abdominal lesions,accumulation of experience and further studies are needed.
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Memo
收稿日期:2018-05-07。
基金项目:中国工程院咨询项目（编号：2019-XY-34）
通讯作者:王焕民,Email:hamiwang@aliyun.com