Liu Xin,Liu Ge,Yang Yi.Predicative factors and optimal timing for surgical repair in children with primary vesicoureteral reflux[J].Journal of Clinical Pediatric Surgery,,18():830-834.[doi:10.3969/j.issn.1671-6353.2019.10.006]
Predicative factors and optimal timing for surgical repair in children with primary vesicoureteral reflux
- CLC:
- R726.9;R693;R699.4
- Abstract:
- Objective To explore the relevant predicative factors and optimal surgical timing in children undergoing corrective surgery for vesicoureteral reflux (VUR).Methods A retrospective study was conducted for 84 children undergoing open surgical repair for VUR from November 2012 to June 2019. Clinical characteristics were collected for identifying the predictors of surgical interventions. And univariate and multivariable analyses were performed using the SPSS version 19 software package. Results Among them,24 cases (28.6%) underwent intravesical ureteroneocystostomy while another 60 (71.4%) were managed conservatively. Based upon multivariable analyses,age,gender,febrile urinary tract infections,maximal grade of reflux,prenatal hydronephrosis and VUR phase of voiding cystourethrogram were not the predictors of eventual surgery. Ureteral dilatation[OR=2.26,95%CI(1.27-4.00)] and maximal grade of reflux[OR=35.70,95%CI(2.87-444.77)] were among the strongest predictors of surgical interventions.Conclusion Higher grades of VUR and ureteral dilatation >7.65 mm were the strongest predictors of eventual surgical interventions.
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Memo
收稿日期:2019-09-19。
基金项目:国家自然科学基金（编号：81571514）
通讯作者:杨屹,Email:yangy2@sj-hospital.org