Ning Feng,He Jun,Tu Lei,et al.Eosinophilic cystitis of children:a report of two cases.[J].Journal of Clinical Pediatric Surgery,,17():379-382.
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Eosinophilic cystitis of children:a report of two cases.

Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R] volume: 第17卷 Number: 2018 05 Page: 379-382 Column: 论著 Date of publication: 2018-05-28
Author(s):
Ning Feng; He Jun; Tu Lei; Hu Janjun; Chen Weijian; Zhao Yaowang.
Hunan Children’s Hospital,Changsha 410007,China
Keywords:
Cystitis;  Oxyphil Cells;  Pathology;  Biopsy;  Child
Document code:
A
Abstract:
ObjectiveTo explore the clinical features,pathological examinations and treatments of eosinophilic cystitis.MethodsTwo male cases of eosinophilic cystitis were reviewed from January 2016 to March 2017.ResultsCase 1,6yearold,had intermittent hematuria with urinary frequency,urgency,difficult urination and abdominal pain;Case 2,7yearold,complained of urinary frequency,urgency,urine pain,dysuria and pubic bone pain.Neither had any history of allergy.Counts of eosinophils increased obviously.Bone marrow biopsy indicated eosinophil increased,urine culture was negative,urine microscopy examination,6yearold boy of every 20 to 25 red blood cells at a high magnification and household dust mites (D1D2) level 2 IU/ml.Ultrasound,computed tomography (CT) and cystography showed that bladder wall became thickened obviously with diffuse mucosal lesions.Microscopic examination indicated bladder capacity decreased and there was no occupying lesion.Mucosal redness was found at bottom and neck of bladder.And biopsy pathology revealed mucosal edema,numerous eosinophils infiltrating through intrinsic muscle layer and focal necrosis.Case 1 received cetirizine hydrochloride supplemented by 6week decreasing doses of prednisone treatment while case 2 had cetirizine hydrochloride alone.During a postoperative followup period of 6 months,abnormal symptoms of micturition disappeared.Neither ultrasound nor CT revealed no wall thickening or occupying lesions.ConclusionEosinophilic cystitis is rare in children.Easily misdiagnosed as nonspecific inflammation and bladder occupying lesions,it is definitely diagnosed by cystoscopy and biopsy pathology.Antiinflammatory,antiallergic and cortical hormone nonspecific drugs are routinely offered.
Last Update: 2018-05-23