Wu Shuihua.Classification characteristics and management strategies of germinal matrix-intraventricular hemorrhage in preterm infants[J].Journal of Clinical Pediatric Surgery,,():107-110.[doi:10.3760/cma.j.cn101785-20251029-00024]
Classification characteristics and management strategies of germinal matrix-intraventricular hemorrhage in preterm infants
- Keywords:
- Preterm; Germinal Matrix-Intraventricular Hemorrhage; Posthemorrhagic Hydrocephalus; Microsurgery; Ventriculoperitoneal Shunt; Neurodevelopmental Outcome; Ventricular Index
- Abstract:
- With advances in perinatal medicine and neonatal intensive care technologies,the survival rates of extremely preterm infants and extremely low birth weight infants have increased significantly; however,brain injury in preterm infants remains a major constraint on long-term quality of survival.Germinal matrix-intraventricular hemorrhage (GMH-IVH) and its secondary complications,including posthemorrhagic ventricular dilatation (PHVD) and posthemorrhagic hydrocephalus (PHH),are the leading causes of cerebral palsy,cognitive impairment,and epilepsy in survivors.The clinical diagnosis and management of GMH-IVH require multidisciplinary collaboration.Key current challenges include elucidating the pathological essence through imaging-based classification,determining the optimal timing for surgical intervention using quantitative indicators,and formulating individualized drainage strategies.Integrating the latest domestic and international evidence-based medical data,this article provides an in-depth analysis from a neurosurgical perspective of the pathophysiological mechanisms and classification connotations of GMH-IVH,and constructs a sequential assessment system based on multiparametric quantitative transcranial ultrasonography.In terms of treatment strategies,a "stepwise" management approach is advocated according to disease progression,ranging from bundled monitoring and temporary cerebrospinal fluid drainage to permanent shunting,thereby providing a reference for the standardized diagnosis and treatment of GMH-IVH in preterm infants.
References:
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Memo
收稿日期:2025-10-29。
基金项目:湖南省自然科学基金(2025JJ50682)
通讯作者:吴水华,Email:292454021@qq.com