Cao Jun,Li Haichong.Clinical diagnostics and interventions of children with neurofibromatosis type 1 associated scoliosis[J].Journal of Clinical Pediatric Surgery,2025,(04):301-306.[doi:10.3760/cma.j.cn101785-202412060-001]
Clinical diagnostics and interventions of children with neurofibromatosis type 1 associated scoliosis
- Keywords:
- Neurofibromatosis Type 1; Scoliosis; Diagnosis; Surgical Procedures; Operative; Conservative Treatment; Drug Therapy; Multi－disciplinary Team; Child
- Abstract:
- Children of type 1 neurofibromatosis may present with a wide range of symptoms,including café au lait spots,plexiform neurofibromas and skeletal system deformities.Among them,scoliosis is the most common skeletal deformity.Children with NF1 scoliosis often have nutritional deficiency-type changes in spinal bones,leading to early onset and rapid progression of scoliosis,causing deformity of appearance and affecting normal growth and development of spine.Thus early intervention is necessary.Based on the location,type,degree of scoliosis,and patient age and growth potential,appropriate treatments may be selected.In addition to treating scoliosis,attention should also be paid to managing concomitant deformities and preventing complications.For overall management of NF1,multidisciplinary treatment is needed to provide standardized,individual- ized and meticulous treatment.
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Memo
收稿日期:2024-12-25。
基金项目:北京市自然科学基金-海淀原始创新联合基金资助项目（L222095）;国家重点研发计划资助（2023YFC2507701）
通讯作者:曹隽,Email:caojunhere@yeah.com