Shi Boyi,Peng Wei.Research progress on left heart decompression strategies in venoarterial extracorporeal membrane oxygenation[J].Journal of Clinical Pediatric Surgery,2025,(03):282-287.[doi:10.3760/cma.j.cn101785-202407043-015]
Research progress on left heart decompression strategies in venoarterial extracorporeal membrane oxygenation
- Keywords:
- Veno-arterial Extracorporeal Membrane Oxygenation; Left Ventricle Unloading; Left Ventricular Dilation; Surgical Procedures; Operative; Child
- Abstract:
- Venoarterial extracorporeal membrane oxygenation (V-A ECMO) is primarily used to provide circulatory and respiratory support in patients with severe cardiogenic shock or refractory cardiac arrest.Although it allows the heart to rest for a certain period,the increased left ventricular afterload in some patients can lead to left ventricular dilation,exacerbating myocardial damage and pulmonary edema,which contradicts the fundamental principles of ECMO.Therefore,an appropriate and effective left heart decompression strategy is essential for patients receiving V-A ECMO.This review summarizes the latest research progress on mechanical left heart decompression strategies in V-A ECMO.
References:
[1] Ventetuolo CE,Muratore CS.Extracorporeal life support in critically ill adults[J].Am J Respir Crit Care Med,2014,190(5):497-508.DOI:10.1164/rccm.201404-0736CI.
[2] 闫阳波,干昌平.心源性休克患者外周静脉-动脉体外膜肺氧合支持下左心减压的相关问题[J].中国胸心血管外科临床杂志,2021,28(9):1114-1118.DOI:10.7507/1007-4848.202011090. Yan YB,Gan CP.Issues on left ventricular decompression during veno-arterial extracorporeal membrane oxygenation in cardiogenic shock patients[J].Chin J Clin Thorac Cardiovasc Surg,2021,28(9):1114-1118.DOI:10.7507/1007-4848.202011090.
[3] Kawashima D,Gojo S,Nishimura T,et al.Left ventricular mechanical support with Impella provides more ventricular unloading in heart failure than extracorporeal membrane oxygenation[J].ASAIO J,2011,57(3):169-176.DOI:10.1097/MAT.0b013e31820e121c.
[4] Makdisi G,Hashmi ZA,Wozniak TC,et al.Left ventricular thrombus associated with arteriovenous extra corporeal membrane oxygenation[J].J Thorac Dis,2015,7(11):E552-E554.DOI:10.3978/j.issn.2072-1439.2015.11.18.
[5] Cheng A,Swartz MF,Massey HT.Impella to unload the left ventricle during peripheral extracorporeal membrane oxygenation[J].ASAIO J,2013,59(5):533-536.DOI:10.1097/MAT.0b013e31829f0e52.
[6] Rupprecht L,Fl?rchinger B,Schopka S,et al.Cardiac decompression on extracorporeal life support:a review and discussion of the literature[J].ASAIO J,2013,59(6):547-553.DOI:10.1097/MAT.0b013e3182a4b2f6.
[7] 牛欢,詹峰,欧阳艳红.静脉-动脉体外膜肺氧合中左心室减压策略[J].中国临床新医学,2021,14(5):450-454.DOI:10.3969/j.issn.1674-3806.2021.05.06. Niu H,Zhan F,Ouyang YH.Strategy of left ventricular decompression in venoarterial extracorporeal membrane oxygenation[J].Chin J New Clin Med,2021,14(5):450-454.DOI:10.3969/j.issn.1674-3806.2021.05.06.
[8] Ro SK,Kim JB,Jung SH,et al.Extracorporeal life support for cardiogenic shock:influence of concomitant intra-aortic balloon counterpulsation[J].Eur J Cardiothorac Surg,2014,46(2):186-192.DOI:10.1093/ejcts/ezu005.
[9] Rastan AJ,Dege A,Mohr M,et al.Early and late outcomes of 517 consecutive adult patients treated with extracorporeal membrane oxygenation for refractory postcardiotomy cardiogenic shock[J].J Thorac Cardiovasc Surg,2010,139(2):302-311.e1.DOI:10.1016/j.jtcvs.2009.10.043.
[10] Russo JJ,Aleksova N,Pitcher I,et al.Left ventricular unloading during extracorporeal membrane oxygenation in patients with cardiogenic shock[J].J Am Coll Cardiol,2019,73(6):654-662.DOI:10.1016/j.jacc.2018.10.085.
[11] Kowalewski M,Malvindi PG,Zieliński K,et al.Left ventricle unloading with veno-arterial extracorporeal membrane oxygenation for cardiogenic shock.Systematic review and meta-analysis[J].J Clin Med,2020,9(4):1039.DOI:10.3390/jcm9041039.
[12] Al-Fares AA,Randhawa VK,Englesakis M,et al.Optimal strategy and timing of left ventricular venting during veno-arterial extracorporeal life support for adults in cardiogenic shock:a systematic review and meta-analysis[J].Circ Heart Fail,2019,12(11):e006486.DOI:10.1161/CIRCHEARTFAILURE.119.006486.
[13] Donker DW,Brodie D,Henriques JPS,et al.Left ventricular unloading during veno-arterial ECMO:a simulation study[J].ASAIO J,2019,65(1):11-20.DOI:10.1097/MAT.0000000000000755.
[14] Dangl M,Albosta M,Butros H,et al.Temporary mechanical circulatory support:left,right,and biventricular devices[J].Curr Cardiol Rev,2023,19(5):27-42.DOI:10.2174/1573403X19666230314115853.
[15] Nishimura T,Hirata Y,Ise T,et al.JCS/JSCVS/JCC/CVIT 2023 guideline focused update on indication and operation of PCPS/ECMO/IMPELLA[J].Circ J,2024,88(6):1010-1046.DOI:10.1253/circj.CJ-23-0698.
[16] Motia N,Marko V,Karlsen MMW.Complications associated with intra-aortic balloon pump treatment in critically ill patients:a systematic review[J].Nurs Crit Care,2024,29(6):1768-1780.DOI:10.1111/nicc.13163.
[17] Ibanez B,James S,Agewall S,et al.2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation:the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC)[J].Eur Heart J,2018,39(2):119-177.DOI:10.1093/eurheartj/ehx393.
[18] Meani P,Gelsomino S,Natour E,et al.Modalities and effects of left ventricle unloading on extracorporeal life support:a review of the current literature[J].Eur J Heart Fail,2017,19(S2):84-91.DOI:10.1002/ejhf.850.
[19] Alhussein M,Osten M,Horlick E,et al.Percutaneous left atrial decompression in adults with refractory cardiogenic shock supported with veno-arterial extracorporeal membrane oxygenation[J].J Card Surg,2017,32(6):396-401.DOI:10.1111/jocs.13146.
[20] Eastaugh LJ,Thiagarajan RR,Darst JR,et al.Percutaneous left atrial decompression in patients supported with extracorporeal membrane oxygenation for cardiac disease[J].Pediatr Crit Care Med,2015,16(1):59-65.DOI:10.1097/PCC.0000000000000276.
[21] Baruteau AE,Barnetche T,Morin L,et al.Percutaneous balloon atrial septostomy on top of venoarterial extracorporeal membrane oxygenation results in safe and effective left heart decompression[J].Eur Heart J Acute Cardiovasc Care,2018,7(1):70-79.DOI:10.1177/2048872616675485.
[22] Welker CC,Huang J,Boswell MR,et al.Left ventricular decompression in VA-ECMO:analysis of techniques and outcomes[J].J Cardiothorac Vasc Anesth,2022,36(11):4192-4197.DOI:10.1053/j.jvca.2022.07.024.
[23] Haynes S,Kerber RE,Johnson FL,et al.Left heart decompression by atrial stenting during extracorporeal membrane oxygenation[J].Int J Artif Organs,2009,32(4):240-242.DOI:10.1177/039139880903200408.
[24] Veeram Reddy SR,Guleserian KJ,Nugent AW.Transcatheter removal of atrial septal stent placed to decompress left atrium with VA ECMO[J].Catheter Cardiovasc Interv,2015,85(6):1021-1025.DOI:10.1002/ccd.25817.
[25] Xie A,Forrest P,Loforte A.Left ventricular decompression in veno-arterial extracorporeal membrane oxygenation[J].Ann Cardiothorac Surg,2019,8(1):9-18.DOI:10.21037/acs.2018.11.07.
[26] Delmas C,Vallee L,Bouisset F,et al.Use of percutaneous atrioseptotosmy for left heart decompression during veno-arterial extracorporeal membrane oxygenation support:an observational study[J].J Am Heart Assoc,2022,11(17):e024642.DOI:10.1161/JAHA.121.024642.
[27] Baldetti L,Gallone G.Left ventricular unloading and venting in veno-arterial extracorporeal membrane oxygenation:the importance of cardiogenic shock aetiology in guiding treatment strategies[J].ESC Heart Fail,2024,11(2):615-618.DOI:10.1002/ehf2.14717.
[28] Haertel F,Lehmann T,Heller T,et al.Impact of a VA-ECMO in combination with an extracorporeal cytokine hemadsorption system in critically ill patients with cardiogenic shock-design and rationale of the ECMOsorb trial[J].J Clin Med,2023,12(15):4893.DOI:10.3390/jcm12154893.
[29] Ezad SM,Ryan M,Donker DW,et al.Unloading the left ventricle in venoarterial ECMO:in whom,when,and how?[J].Circulation,2023,147(16):1237-1250.DOI:10.1161/CIRCULATIONAHA.122.062371.
[30] Colombo T,Garatti A,Bruschi G,et al.First successful bridge to recovery with the Impella Recover 100 left ventricular assist device for fulminant acute myocarditis[J].Ital Heart J,2003,4(9):642-645.
[31] Lim HS.The effect of impella CP on cardiopulmonary physiology during venoarterial extracorporeal membrane oxygenation support[J].Artif Organs,2017,41(12):1109-1112.DOI:10.1111/aor.12923.
[32] Eliet J,Gaudard P,Zeroual N,et al.Effect of Impella during veno-arterial extracorporeal membrane oxygenation on pulmonary artery flow as assessed by end-tidal carbon dioxide[J].ASAIO J,2018,64(4):502-507.DOI:10.1097/MAT.0000000000000662.
[33] Karatolios K,Chatzis G,Markus B,et al.Biventricular unloading in patients with refractory cardiogenic shock[J].Int J Cardiol,2016,222:247-252.DOI:10.1016/j.ijcard.2016.07.227.
[34] Pappalardo F,Schulte C,Pieri M,et al.Concomitant implantation of Impella?on top of veno-arterial extracorporeal membrane oxygenation may improve survival of patients with cardiogenic shock[J].Eur J Heart Fail,2017,19(3):404-412.DOI:10.1002/ejhf.668.
[35] Schrage B,Becher PM,Bernhardt A,et al.Left ventricular unloading is associated with lower mortality in patients with cardiogenic shock treated with venoarterial extracorporeal membrane oxygenation:results from an international,multicenter cohort study[J].Circulation,2020,142(22):2095-2106.DOI:10.1161/CIRCULATIONAHA.120.048792.
[36] Radakovic D,Zittermann A,Rojas SV,et al.Left ventricular unloading in patients on venoarterial extracorporeal membrane oxygenation therapy in cardiogenic shock:prophylactic versus bail-out strategy[J].Life (Basel),2023,13(2):582.DOI:10.3390/life13020582.
[37] Bastos MB,van Wiechen MP,Van Mieghem NM,et al.PulseCath iVAC2L:next-generation pulsatile mechanical circulatory support[J].Future Cardiol,2020,16(2):103-112.DOI:10.2217/fca-2019-0060.
[38] Travis AR,Giridharan GA,Pantalos GM,et al.Vascular pulsatility in patients with a pulsatile-or continuous-flow ventricular assist device[J].J Thorac Cardiovasc Surg,2007,133(2):517-524.DOI:10.1016/j.jtcvs.2006.09.057.
[39] Keeble TR,Karamasis GV,Rothman MT,et al.Percutaneous haemodynamic and renal support in patients presenting with decompensated heart failure:a multi-centre efficacy study using the Reitan Catheter Pump (RCP)[J].Int J Cardiol,2019,275:53-58.DOI:10.1016/j.ijcard.2018.09.085.
[40] Seyfarth M,Sibbing D,Bauer I,et al.A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock caused by myocardial infarction[J].J Am Coll Cardiol,2008,52(19):1584-1588.DOI:10.1016/j.jacc.2008.05.065.
[41] Kamada K,Joko K,Otaka N,et al.Successful treatment of acute left main coronary artery disease with a drug-coated balloon under left ventricular unloading using Impella:a case report[J].Eur Heart J Case Rep,2024,8(9):ytae443.DOI:10.1093/ehjcr/ytae443.
[42] Schrage B,Ibrahim K,Loehn T,et al.Impella support for acute myocardial infarction complicated by cardiogenic shock[J].Circulation,2019,139(10):1249-1258.DOI:10.1161/CIRCULATIONAHA.118.036614.
[43] Pieri M,Sorrentino T,Oppizzi M,et al.The role of different mechanical circulatory support devices and their timing of implantation on myocardial damage and mid-term recovery in acute myocardial infarction related cardiogenic shock[J].J Interv Cardiol,2018,31(6):717-724.DOI:10.1111/joic.12569.
[44] Saito S,Okubo S,Matsuoka T,et al.Impella-current issues and future expectations for the percutaneous,microaxial flow left ventricular assist device[J].J Cardiol,2024,83(4):228-235.DOI:10.1016/j.jjcc.2023.10.008.
[45] Na SJ,Yang JH,Yang JH,et al.Left heart decompression at venoarterial extracorporeal membrane oxygenation initiation in cardiogenic shock:prophylactic versus therapeutic strategy[J].J Thorac Dis,2019,11(9):3746-3756.DOI:10.21037/jtd.2019.09.35.
[46] Yang JH,Kim JW,Kang DH,et al.Additional extracorporeal membrane oxygenation pump without an oxygenator for transseptal left atrial decompression:a case report[J].ASAIO J,2023,69(7):e360-e362.DOI:10.1097/MAT.0000000000001904.
[47] Alkhouli M,Narins CR,Lehoux J,et al.Percutaneous decompression of the left ventricle in cardiogenic shock patients on venoarterial extracorporeal membrane oxygenation[J].J Card Surg,2016,31(3):177-182.DOI:10.1111/jocs.12696.
[48] Bréchot N,Demondion P,Santi F,et al.Intra-aortic balloon pump protects against hydrostatic pulmonary oedema during peripheral venoarterial-extracorporeal membrane oxygenation[J].Eur Heart J Acute Cardiovasc Care,2018,7(1):62-69.DOI:10.1177/2048872617711169.
[49] Aiyagari RM,Rocchini AP,Remenapp RT,et al.Decompression of the left atrium during extracorporeal membrane oxygenation using a transseptal cannula incorporated into the circuit[J].Crit Care Med,2006,34(10):2603-2606.DOI:10.1097/01.CCM.0000239113.02836.F1.
[50] Yamamoto M,Oshima Y,Matsuhisa H,et al.Left atrial decompression by minithoracotomy during extracorporeal life support[J].Ann Thorac Surg,2019,107(3):e227-e228.DOI:10.1016/j.athoracsur.2018.07.084.
[51] Rao P,Mosier J,Malo J,et al.Peripheral VA-ECMO with direct biventricular decompression for refractory cardiogenic shock[J].Perfusion,2018,33(6):493-495.DOI:10.1177/0267659118761558.
[52] Guirgis M,Kumar K,Menkis AH,et al.Minimally invasive left-heart decompression during venoarterial extracorporeal membrane oxygenation:an alternative to a percutaneous approach[J].Interact Cardiovasc Thorac Surg,2010,10(5):672-674.DOI:10.1510/icvts.2009.228346.
[53] Fumagalli R,Bombino M,Borelli M,et al.Percutaneous bridge to heart transplantation by venoarterial ECMO and transaortic left ventricular venting[J].Int J Artif Organs,2004,27(5):410-413.DOI:10.1177/039139880402700510.
[54] Kang J,Lee KS,Lee HS,et al.Differential effect of left ventricular unloading according to the aetiology of cardiogenic shock[J].ESC Heart Fail,2024,11(1):338-348.DOI:10.1002/ehf2.14584.
[55] Sundermeyer J,Kellner C,Beer BN,et al.Sex-related differences in patients presenting with heart failure-related cardiogenic shock[J].Clin Res Cardiol,2024,113(4):612-625.DOI:10.1007/s00392-024-02392-8.
[56] Rabah H,Rabah A.Extracorporeal membrane oxygenation (ECMO):what we need to know[J].Cureus,2022,14(7):e26735.DOI:10.7759/cureus.26735.
[57] Wang HW,Li CL,Li D,et al.Efficacy of venoarterial extracorporeal membrane oxygenation with and without intra-aortic balloon pump in adult cardiogenic shock[J].Front Cardiovasc Med,2024,11:1431875.DOI:10.3389/fcvm.2024.1431875.
[58] Choudhury TA,Ofori-Amanfo G,Choi J,et al.Left heart decompression on veno-arterial extracorporeal membrane oxygenation in children with dilated cardiomyopathy and myocarditis:an extracorporeal life support organization registry review[J].Pediatr Crit Care Med,2021,22(12):1026-1032.DOI:10.1097/PCC.0000000000002775.
[59] Lin YJ,Liu HY,Kuo HC,et al.Left ventricle decompression strategies in pediatric peripheral extracorporeal membrane oxygenation[J].Acta Cardiol Sin,2019,35(3):335-341.DOI:10.6515/ACS.201905_35(3).20181125A.
[60] Becher PM,Schrage B,Sinning CR,et al.Venoarterial extracorporeal membrane oxygenation for cardiopulmonary support[J].Circulation,2018,138(20):2298-2300.DOI:10.1161/CIRCULATIONAHA.118.036691.
Memo
收稿日期:2024-7-18。
基金项目:江苏省妇幼保健协会科研项目(FYX202201)
通讯作者:彭卫,Email:pwking@sina.com