Feng Yong,Zhou Chonggao,Xia Renpeng,et al.A comparative study of total laparoscopic versus open Kasai portoenterostomy for type Ⅲ biliary atresia[J].Journal of Clinical Pediatric Surgery,2025,(03):231-235.[doi:10.3760/cma.j.cn101785-202405073-006]
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A comparative study of total laparoscopic versus open Kasai portoenterostomy for type Ⅲ biliary atresia

Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R] volume: Number: 2025年03 Page: 231-235 Column: 论著 Date of publication: 2025-03-28
Author(s):
Feng Yong1;  Zhou Chonggao1;  Xia Renpeng1;  Zou Chanjuan1;  Xu Guang1;  Dong Jie2;  Li Bo1
1. Fetal and Neonatal Surgery, Affiliated Children’s Hospital, Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha 410007, China;
2. Institute of Pediatric Medicine, Affiliated Children’s Hospital, Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha 410007, China
Keywords:
Laparoscopy; Biliary Atresia; Surgical Procedures;  Operative; Child
DOI:
10.3760/cma.j.cn101785-202405073-006
Abstract:
Objective To compare the efficacy of total laparoscopic versus open Kasai portoenterostomy for type Ⅲ biliary atresia (BA).Methods From May 2020 to December 2021,the relevant clinical data were retrospectively reviewed for 14 children undergoing laparoscopic Kasai portoenterostomy and 66 cases undergoing open Kasai portoenterostomy.Two groups were compared with regards to gender,operative age,body weight,preoperative total bilirubin,direct bilirubin,alanine aminotransferase,gamma-glutamyl transferase,aspartate aminotransferase-to-platelet ratio index,operative duration,volume of blood loss,time of feeding recovery,postoperative hospitalization stay,postoperative complications (biliary fistula,intestinal fistula,intestinal obstruction & wound dehiscence),postoperative cholangitis rate,early cholangitis rate,frequent cholangitis rate,jaundice clearance rate,1/2-year survival rate of native liver (SNL) and survival rate.Results There was statistically significant inter-group difference (P<0.05) in operative duration .No statistically significant difference (P>0.05) existed in volume of blood loss,time of feeding recovery,postoperative hospitalization stay,postoperative cholangitis rate (71.4% vs.48.5%),early cholangitis rate (28.6% vs.19.7%),frequent cholangitis rate (14.3% vs.15.2%),jaundice clearance rate (71.4% vs.69.7%),1-year SNL (57.1% vs.75.8%),2-year SNL (57.1% vs.71.2%),1-year survival rate (78.6% vs.84.8%) and 2-year survival rate (78.6% vs.81.8%).Conclusions Total laparoscopic Kasai portoenterostomy is safe,feasible and mini-invasive.Its outcomes are superior to those of open surgery.

References:

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Memo

收稿日期:2024-5-28。
基金项目:国家临床重点专科重大科研专项(Z20230059);湖南省出生缺陷协同防治科技重大专项(2019SK1010);湖南省自然科学基金(2025JJ50672)
通讯作者:周崇高,Email:zhouchonggao@sina.com

Last Update: 2025-03-28