Wang Peixin,Zhao Jun,Wang Xingsheng,et al.Research advances the correlation between adolescent idiopathic scoliosis and paravertebral muscle imbalance[J].Journal of Clinical Pediatric Surgery,,():898-900.[doi:10.3760/cma.j.cn101785-202302028-018]
Research advances the correlation between adolescent idiopathic scoliosis and paravertebral muscle imbalance
- Keywords:
- Adolescent Idiopathic Scoliosis; Muscle Development; Dystonia; Ladybird Homeobox 1; Paired Box 3
- Abstract:
- As a three-dimensional spinal deformity consisting of lateral deviation and axial rotation of spine,adolescent idiopathic scoliosis (AIS) is the most common generalized musculoskeletal disorder affecting the development of spine.The influencing factors of AIS are rather diverse and complex.It has a serious impact on the quality-of-life and physical and mental health of children and adolescents.Especially the influence of paraspinal muscles on AIS has attracted growing attention from clinicians.This review summarized the effects of ladybird homeobox 1 (LBX1),paired box 3 (PAX3) and estrogen on paraspinal muscles,as well as the effects of muscle volume and fat infiltration on the occurrence and development of AIS.It shall provide some conceptual frameworks for elucidating the pathogenesis of scoliosis and a proper clinical treatment of scoliosis.
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Memo
收稿日期:2023-2-18。
基金项目:省级重点人才项目(甘组通字【2022】77号);联合科研基金重大项目(23JRRA1529)
通讯作者:赵军,Email:673078008@qq.com